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Ying-**n Qi
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Article
Open AccessHuman cytomegalovirus infection impairs neural differentiation via repressing sterol regulatory element binding protein 2-mediated cholesterol biosynthesis
Congenital human cytomegalovirus (HCMV) infection is a major cause of abnormalities and disorders in the central nervous system (CNS) and/or the peripheral nervous system (PNS). However, the complete pathogene...
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Open AccessAssociation of serum interleukin-2 with severity and prognosis in hospitalized patients with community-acquired pneumonia: a prospective cohort study
The prior studies have shown that interleukin-2 (IL-2) exerts important roles in the pathological and physiological processes of lung diseases. However, the role of IL-2 in community-acquired pneumonia (CAP) i...
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Estimating Individualized Treatment Regimes to Optimize Incremental Cost-Effectiveness Ratio
Medical decision making can be challenging due to the trade-off between improving clinical efficacy and the associated medical costs. Evaluation of the incremental cost-effectiveness ratio (ICER) of different ...
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Open AccessOptimizing anterior urethral stricture assessment: leveraging AI-assisted three-dimensional sonourethrography in clinical practice
This investigation sought to validate the clinical precision and practical applicability of AI-enhanced three-dimensional sonographic imaging for the identification of anterior urethral stricture.
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Combined Analysis of the Metabolome and Transcriptome Sheds New Light on the Mechanisms of Seed Maturation in Amorphophallus muelleri
Amorphophallus muelleri, a naturally occurring variant of the commercially valuable Amorphophallus species grown in Southeast Asia, stands out for its desirable traits: high konjac glucomannan (KGM) content, apom...
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Long-term observation of V4c implantable collamer lenses implantation for moderate to extreme high myopia correction: five years follow-up
This study aims to assess the long term effectiveness, safety, predictability and stability of V4c implantable collamer lenses (ICL) for correction of moderate to extreme high myopia.
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Metal complexes of bipyridine-functionalized covalent organic frameworks as efficient electrocatalysts for oxygen evolution reaction
Electrocatalytic water splitting is considered a clean and practical method for producing energy. In this study, COF-Bpy, a bipyridine-functionalized covalent organic framework (COF), was prepared via post-syn...
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Open AccessAcoustic spin-controlled orbital rotations in double spiral acoustic beams
Similar to optical spin-orbit interactions (SOIs), acoustic SOIs are anticipated to offer fresh perspectives and capabilities for acoustic manipulation beyond conventional scalar degrees of freedom. However, t...
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Open AccessEffects of Staphylococcus aureus on stem cells and potential targeted treatment of inflammatory disorders
Due to the advanced studies on stem cells in developmental biology, the roles of stem cells in the body and their phenotypes in related diseases have not been covered clearly. Meanwhile, with the intensive res...
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Novel Mutation in the Moesin (MSN) Gene Leads to Immunodeficiency with Epstein–Barr Virus (EBV) Infection and Dermatomyositis-Like Symptoms
Moesin (MSN) deficiency is a recently reported combined immunodeficiency, and few cases have been reported to date. We describe a Chinese patient with a novel mutation causing MSN deficiency and a novel phenot...
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Structural and electronic properties of clathrate-like hydride: MH6 and MH9 (M = Sc, Y, La)
The addition of central metal atoms to hydrogen clathrate structures is thought to provide a certain amount of “internal chemical pressure” to offset some of the external physical pressure required for compoun...
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Inflammation-Responsive Mesoporous Silica Nanoparticles with Synergistic Anti-inflammatory and Joint Protection Effects for Rheumatoid Arthritis Treatment
Joint destruction is a major burden and an unsolved problem in rheumatoid arthritis (RA) patients. We designed an intra-articular mesoporous silica nanosystem (MSN-TP@PDA-GlcN) with anti-inflammatory and joint...
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Advanced glycosylation end products promote the progression of CKD-MBD in rats, and its natural inhibitor, quercetin, mitigates disease progression
Chronic kidney disease–mineral and bone metabolism disorder (CKD-MBD) is a common chronic kidney disease (CKD)-associated complication that increases the risk of metabolic bone diseases, fractures, osteoblasti...
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Open AccessMulti-domain fusion for cargo UAV fault diagnosis knowledge graph construction
The fault diagnosis of cargo UAVs (Unmanned Aerial Vehicles) is crucial to ensure the safety of logistics distribution. In the context of smart logistics, the new trend of utilizing knowledge graph (KG) for fa...
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Superhydrophilic Self-supported Perovskite Oxides for Oxygen Evolution Reactions in Oilfield Wastewater
Develo** highly efficient catalysts for oxygen evolution reactions (OER) in complex water environments is crucial for promoting the photovoltaic electrolysis of water splitting for hydrogen production in ari...
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Open AccessSensory ASIC3 channel exacerbates psoriatic inflammation via a neurogenic pathway in female mice
Psoriasis is an immune-mediated skin disease associated with neurogenic inflammation, but the underlying molecular mechanism remains unclear. We demonstrate here that acid-sensing ion channel 3 (ASIC3) exacerb...
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Open AccessThe effect of cadre–farmer relationship on farmers’ willingness to treat domestic waste: evidence from China
The construction of an ecologically livable rural environment requires treating rural domestic waste. Farmers, as key participants in rural domestic waste disposal, can improve the rural environment by disposi...
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Machine learning guided efficiency improvement for Sn-based perovskite solar cells with efficiency exceeding 20%
Eco-friendly lead-free tin (Sn)-based perovskites have drawn much attention in the field of photovoltaics, and the highest power conversion efficiency (PCE) of Sn-based perovskite solar cells (PSCs) has been r...
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Open AccessAugmented microglial endoplasmic reticulum-mitochondria contacts mediate depression-like behavior in mice induced by chronic social defeat stress
Extracellular ATP (eATP) signaling through the P2X7 receptor pathway is widely believed to trigger NLRP3 inflammasome assembly in microglia, potentially contributing to depression. However, the cellular stress...
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Open AccessBiomechanical comparison of the therapeutic effect of a novel proximal femoral bionic intramedullary nail and traditional inverted triangle hollow screw on femoral neck fracture
A novel Proximal Femoral Bionic Nail (PFBN) has been developed by a research team for the treatment of femoral neck fractures. This study aims to compare the biomechanical properties of the innovative PFBN wit...
