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Article

The activation of c-Jun NH₂-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells

c-Jun NH2-terminal kinases (JNKs) are strongly activated by a stressful cellular environment, such as chemotherapy and oxidative stress. Autophagy is a protein-degradation system in which double-membrane vacuo...

Guang Jia, Rui Kong, Zhi-Bin Ma, Bing Han… in Journal of Experimental & Clinical Cancer … (2014)