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  1. No Access

    Article

    Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning

    Light-field microscopy has emerged as a technique of choice for high-speed volumetric imaging of fast biological processes. However, artifacts, nonuniform resolution and a slow reconstruction speed have limite...

    Zhaoqiang Wang, Lanxin Zhu, Hao Zhang, Guo Li, Chengqiang Yi, Yi Li… in Nature Methods (2021)

  2. No Access

    Protocol

    In Vivo Clonal Analysis of Cardiomyocytes

    The development of the CreER/LoxP system has enabled temporal control and cell type specificity of gene activation or repression. A common application of this system involves lineage tracing and examining the ...

    Ngoc B. Nguyen, G. Esteban Fernandez, Yichen Ding, Tzung Hsiai… in Cardiac Regeneration (2021)

  3. Article

    Open Access

    Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community

    Pseudomonas aeruginosa tends to be among the dominant species in multi-species bacterial consortia in diverse environments. To understand P. aeruginosa’s physiology and interactions with co-existing bacterial spe...

    Yingying Cheng, Joey Kuok Hoong Yam, Zhao Cai, Yichen Ding… in npj Biofilms and Microbiomes (2019)

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  4. Article

    Open Access

    Acquisition of resistance to carbapenem and macrolide-mediated quorum sensing inhibition by Pseudomonas aeruginosa via ICETn43716385

    Pseudomonas aeruginosa can cause life-threatening infections in immunocompromised patients. The first-line agents to treat P. aeruginosa infections are carbapenems. However, the emergence of carbapenem-resistant

    Yichen Ding, Jeanette W. P. Teo, Daniela I. Drautz-Moses… in Communications Biology (2018)

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