5 Result(s)
within
Yi-Lin Yan
Life Sciences
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Article
Therapeutic Effect of Deferoxamine on Iron Overload-Induced Inhibition of Osteogenesis in a Zebrafish Model
Osteoporosis results from an imbalance in bone remodeling, in which osteoclastic bone resorption exceeds osteoblastic bone formation. Iron has recently been recognized as an independent risk factor for osteopo...
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Article
Open AccessEvolution of the osteoblast: skeletogenesis in gar and zebrafish
Although the vertebrate skeleton arose in the sea 500 million years ago, our understanding of the molecular fingerprints of chondrocytes and osteoblasts may be biased because it is informed mainly by research ...
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Article
Open AccessMolecular pedomorphism underlies craniofacial skeletal evolution in Antarctic notothenioid fishes
Pedomorphism is the retention of ancestrally juvenile traits by adults in a descendant taxon. Despite its importance for evolutionary change, there are few examples of a molecular basis for this phenomenon. No...
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Article
Open AccessRAD marker microarrays enable rapid map** of zebrafish mutations
We constructed a restriction site associated DNA (RAD) marker microarray to facilitate rapid genetic map** of zebrafish mutations. Using these microarrays with a bulk segregant approach, we localized previou...
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Chapter
Duplication of a portion of human chromosome 20q containing Topoisomerase (Top1)and Snail genes provides evidence on genome expansion and the radiation of teleost fish
Zebrafish has two duplicate copies of many genes present in single copy in the human genome. Most gene duplicates map in duplicate chromosome segments, suggesting that they are the remnants of a whole genome d...
