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  1. No Access

    Article

    HER2 mutations in advanced cervical neuroendocrine carcinoma: implications for trastuzumab deruxtecan therapy

    Recent clinical evidence shows that the antibody-drug conjugate (ADC) trastuzumab deruxtecan (T-DXd) can successfully treat patients with advanced HER2-mutant non-small cell lung cancer (NSCLC). We aimed to ch...

    Wan-Ru Chao, Ming-Yung Lee, Gwo-Tarng Sheu… in Naunyn-Schmiedeberg's Archives of Pharmaco… (2024)

  2. No Access

    Article

    Interleukin-32 plays an essential role in human calcified aortic valve cells

    Interleukin-32 (IL-32) is an inflammatory cytokine produced mainly by T, natural killer, and epithelial cells. Previous studies on IL-32 have primarily investigated its proinflammatory properties. The IL-32 al...

    Chung-Lin Tsai, Ying-Ming Chiu, Yi-Ju Lee, Chin-Tung Hsieh… in European Cytokine Network (2018)

  3. No Access

    Article

    High incidence of acute promyelocytic leukemia specifically induced by N-nitroso-N-methylurea (NMU) in Sprague–Dawley rats

    Carcinogenic agents such as N-methyl-N-nitrosourea can cause tumors. The aims of the present study were to evaluate and classify a subtype of AML (acute myeloid leukemia) that was induced by NMU. According to pre...

    Yun-Ching Chang, Jeng-Dong Hsu, Wea-Lung Lin, Yi-Ju Lee… in Archives of Toxicology (2012)

  4. Article

    Open Access

    Effects of human parvovirus B19 VP1 unique region protein on macrophage responses

    Activity of secreted phospholipase A (sPLA2) has been implicated in a wide range of cellular responses. However, little is known about the function of human parvovirus B19-VP1 unique region (VP1u) with sPLA2 a...

    Bor-Show Tzang, Chun-Ching Chiu, Chun-Chou Tsai, Yi-Ju Lee… in Journal of Biomedical Science (2009)

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