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  1. Article

    Open Access

    Clinical trials of new drugs for Alzheimer disease: a 2020–2023 update

    Alzheimer's disease (AD) is the leading cause of dementia, presenting a significant unmet medical need worldwide. The pathogenesis of AD involves various pathophysiological events, including the accumulation o...

    Li-Kai Huang, Yi-Chun Kuan, Ho-Wei Lin, Chaur-Jong Hu in Journal of Biomedical Science (2023)

  2. No Access

    Article

    Effects of inspiratory muscle training on blood pressure- and sleep-related outcomes in patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials

    Obstructive sleep apnea (OSA) is frequently accompanied by hypertension, resulting in cardiovascular comorbidities. Continuous positive airway pressure is a standard therapy for OSA but has poor adherence. Ins...

    Tzu-Ang Chen, Sheng-Ting Mao, Huei-Chen Lin, Wen-Te Liu, Ka-Wai Tam in Sleep and Breathing (2023)

  3. No Access

    Article

    Associations of overnight changes in body composition with positional obstructive sleep apnea

    Body composition is considered to be associated with obstructive sleep apnea (OSA) severity. This cross-sectional study aimed to examine associations of overnight body composition changes with positional OSA.

    Nguyen Thanh Tung, Shang-Yang Lin, Hoang Ba Dung in Sleep and Breathing (2023)

  4. Article

    Open Access

    Hybrid robot-assisted gait training for motor function in subacute stroke: a single-blind randomized controlled trial

    Robot-assisted gait training (RAGT) is a practical treatment that can complement conventional rehabilitation by providing high-intensity repetitive training for patients with stroke. RAGT systems are usually e...

    Yen-Nung Lin, Shih-Wei Huang, Yi-Chun Kuan in Journal of NeuroEngineering and Rehabilita… (2022)

  5. Article

    Open Access

    Safety and efficacy of endovascular thrombectomy in acute ischemic stroke treated with anticoagulants: a systematic review and meta-analysis

    Endovascular thrombectomy (EVT) is an effective therapy in acute ischemic stroke (AIS) with large vessel occlusion, especially for those who are unsuitable for intravenous thrombolysis. However, the safety and...

    Jia-Hung Chen, Chien-Tai Hong, Chen-Chih Chung, Yi-Chun Kuan in Thrombosis Journal (2022)

  6. Article

    Open Access

    Intravenous immunoglobulin for postpolio syndrome: a systematic review and meta-analysis

    Postpolio syndrome (PPS) is characterized by progressive disabilities that develop decades after prior paralytic poliomyelitis. Because chronic inflammation may be the process underlying the development of PPS...

    Yao-Hsien Huang, Hung-Chou Chen, Kuang-Wei Huang, Po-Chih Chen in BMC Neurology (2015)

  7. No Access

    Article

    Different Peptic Ulcer Bleeding Risk in Chronic Kidney Disease and End-Stage Renal Disease Patients Receiving Different Dialysis

    End stage renal disease (ESRD) patients receiving hemodialysis (HD) have a higher risk of peptic ulcer bleeding (PUB).

    Kuang-Wei Huang, Hsin-Bang Leu, Jiing-Chyuan Luo in Digestive Diseases and Sciences (2014)