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1,405 Result(s)
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Article
Preparation of (S)-epichlorohydrin using a novel halohydrin dehalogenase by selective conformation adjustment
Chiral epichlorohydrin (ECH) is an attractive intermediate for chiral pharmaceuticals and chemicals preparation. The asymmetric synthesis of chiral ECH using 1,3-dicholoro-2-propanol (1,3-DCP) catalyzed by a h...
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Article
ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the olfactory bulb (OB) ...
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Saccharopolyspora mangrovi sp. nov., a novel mangrove soil actinobacterium with distinct metabolic potential revealed by comparative genomic analysis
A novel mangrove soil-derived actinomycete, strain S2-29T, was found to be most closely related to Saccharopolyspora karakumensis 5K548T based on 16 S rRNA sequence (99.24% similarity) and genomic phylogenetic an...
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Article
Open AccessCorrection: Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
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A Study on the Corrosion Behavior of Ti-Containing Weathering Steel in a Simulated Marine Environment
The aim of this study is to evaluate the effect of titanium on the corrosion characteristics of bridge weathering steel plates in marine environments. The corrosion characteristics of steel containing differen...
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Effective multi-scale enhancement fusion method for low-light images based on interest-area perception OCTM and “pixel healthiness” evaluation
Low-light images suffer from low contrast and low dynamic range. However, most existing single-frame low-light image enhancement algorithms are not good enough in terms of detail preservation and color express...
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Sp/sp2 carbon ratio-driven high-throughput screening of electrocatalytic nitrogen reduction performance on transition metal single-atom catalysts
Single-atom catalysts (SACs) have been widely utilized in electrochemical nitrogen reduction reactions (NRR) due to their high atomic utilization and selectivity. Owing to the unique sp/sp2 co-hybridization, grap...
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Open AccessExploring the interplay of psychiatric symptoms, antipsychotic medications, side effects, employment status, and quality of life in Chronic Schizophrenia
Many factors contribute to quality of life (QoL) in patients with schizophrenia, yet limited research examined these factors in patients in China. This cross-sectional study explores subjective QoL and its ass...
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Salvage haploidentical transplantation for graft failure after first haploidentical allogeneic stem cell transplantation: an updated experience
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. However, there are no recommended regimens for second transp...
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Article
Spontaneous anchoring Cl into α-Co(OH)2 as efficient and stable oxygen reduction electrocatalysts for seawater battery
Seawater battery is an advanced energy storage system that enables conversion of chemical energy to electricity by consuming metals, dissolved oxygen and seawater in anode, cathode and electrolyte, respectivel...
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Article
Open AccessNotoginsenoside R1 promotes Lgr5+ stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling
Inflammatory bowel disease (IBD) is characterized by persistent damage to the intestinal barrier and excessive inflammation, leading to increased intestinal permeability. Current treatments of IBD primarily ad...
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Recent advances in Ir/Ru-based perovskite electrocatalysts for oxygen evolution reaction
Oxygen evolution reaction (OER) is a kinetically harsh four-electron anode reaction that requires a large overpotential to provide current and is of great importance in renewable electrochemical technique. Ir/...
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Article
Effect of robbing intensity on reproductive success of Symphytum officinale (Boraginaceae)
The intervention of nectar robbers in plant pollination systems will cause some pollinators to modify their foraging behavior to act as secondary robbers, consequently adopting a mixed foraging strategy. The i...
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Author Correction: Anti-diabetic drug canagliflozin hinders skeletal muscle regeneration in mice
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Author Correction: ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway
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Article
A non-invasive artificial intelligence model for identifying axillary pathological complete response to neoadjuvant chemotherapy in breast cancer: a secondary analysis to multicenter clinical trial
This study aims to develop a stacking model for accurately predicting axillary lymph node (ALN) response to neoadjuvant chemotherapy (NAC) using longitudinal MRI in breast cancer.
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Article
Comparison of totally robotic and totally laparoscopic gastrectomy for gastric cancer: a propensity score matching analysis
With the improvements in laparoscopic or robotic surgical techniques and instruments, a growing number of surgeons have attempted to complete all digestive tract reconstruction intracorporeally; these procedur...
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Open AccessEffect of acupuncture on tic disorder: a randomized controlled clinical trial based on energy metabolomics and infrared thermography
Acupuncture is a method for treating tic disorder. However, there is a lack of sufficient clinical objective basis in regards of its treatment efficacy. Indeed, there are structural abnormalities present in en...
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Open AccessNovel radiopaque ethanol injection: physicochemical properties, animal experiments, and clinical application in vascular malformations
Despite the efficacy of absolute ethanol (EtOH), its radiolucency introduces several risks in interventional therapy for treating vascular malformations. This study aims to develop a novel radiopaque ethanol i...
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Mendelian randomization evidence for the causal effect of mental well-being on healthy aging
Mental well-being relates to multitudinous lifestyle behaviours and morbidities and underpins healthy aging. Thus far, causal evidence on whether and in what pattern mental well-being impacts healthy aging and...