1,649 Result(s)

Article

Cytochrome P450 2E1 polymorphism and nasopharyngeal carcinoma development in Thailand: a correlative study

Nasopharyngeal carcinoma (NPC) is a rare tumor in most parts of the world but occurs at relatively high frequency among people of Chinese descent. The cytochrome P450 2E1 enzyme (CYP2E1) is responsible for the...

Narisorn Kongruttanachok, Sairoong Sukdikul, Surachai Setavarin… in BMC Cancer (2001)

Article

Correction: Overexpression of the thymosin beta-10 gene in human ovarian cancer cells disrupts F-actin stress fiber and leads to apoptosis

Seung-Hoon Lee, Wei Zhang, Jung-Joo Choi, Yong-suk Cho, Sun-Hee Oh… in Oncogene (2002)

Article

Acute Hemorrhagic Rectal Ulcer Syndrome: A New Clinical Entity? Report of 19 Cases and Review of the Literature

Acute hemorrhagic rectal ulcer syndrome is characterized by sudden onset, painless, and massive hemorrhage from rectal ulcer(s) in patients with serious underlying illnesses. It is a matter of controversy whet...

Chang-An Tseng M.D., Li-Tzong Chen M.D.… in Diseases of the Colon & Rectum (2004)

Article

Use of Complementary and Alternative Medicine by Chinese Women with Breast Cancer

Yong Cui, **ao-Ou Shu, Yutang Gao, Wanqing Wen… in Breast Cancer Research and Treatment (2004)

Article

Genotypes and haplotypes of the methyl-CpG-binding domain 2 modify breast cancer risk dependent upon menopausal status

MBD2, the gene encoding methyl-CpG-binding domain (MBD)2, is a major methylation related gene and functions as a transcriptional repressor that can specifically bind to the methylated regions of other genes. MBD2...

Yong Zhu, Heather N Brown, Yawei Zhang, Theodore R Holford… in Breast Cancer Research (2005)

Article

Relationship between cyclooxygenase 8473T>Cpolymorphism and the risk of lung cancer: a case-control study

Cyclooxygenase-2 (COX-2) plays an important role in the development of lung cancer. DNA sequence variations in the COX-2 gene may lead to altered COX-2 production and/or activity, and so they cause inter-individu...

Jung Min Park, ** Eun Choi, Myung Hwa Chae, Won Kee Lee, Sung Ick Cha… in BMC Cancer (2006)

Article

Polymorphisms of XRCC1 genes and risk of nasopharyngeal carcinoma in the Cantonese population

Nasopharyngeal carcinoma (NPC) is one of the most common cancers in southern China. In addition to environmental factors such as Epstein-Barr virus infection and diet, genetic susceptibility has been reported ...

Yun Cao, **ao-** Miao, Ma-Yan Huang, Ling Deng, Li-Fu Hu, Ingemar Ernberg… in BMC Cancer (2006)

Article

Suppression of breast cancer cell growth by Na⁺/H⁺ exchanger regulatory factor 1 (NHERF1)

Na⁺/H⁺ exchanger regulatory factor 1 (NHERF1, also known as EBP50 or NHERF) is a putative tumour suppressor gene in human breast cancer. Located at 17q25.1, NHERF1 is frequently targeted during breast tumourigene...

Yong Pan, Lei Wang, Jia Le Dai in Breast Cancer Research (2006)

Article

Tissue microarray analysis reveals a tight correlation between protein expression pattern and progression of esophageal squamous cell carcinoma

The development of esophageal squamous cell carcinoma (ESCC) progresses a multistage process, collectively known as precursor lesions, also called dysplasia (DYS) and carcinoma in situ (CIS), subsequent invasive ...

Li-yan Xue, Nan Hu, Yong-mei Song, Shuang-mei Zou, Jian-zhong Shou… in BMC Cancer (2006)

Article

In vivo antitumor efficacy and cardiotoxicity of novel anthracycline ID6105 (11-hydroxy-aclacinomycin X, Hyrubicin)

Jung Su Ryu, Hong Sub Lee, Young-Soo Hong… in Cancer Chemotherapy and Pharmacology (2007)

Article

Polymorphisms in the epidermal growth factor receptor gene and the risk of primary lung cancer: a case-control study

Polymorphisms in Epidermal Growth Factor Receptor (EGFR) gene may influence EGFR production and/or activity, thereby modulating susceptibility to lung cancer. To test this hypothesis, we investigated the associat...

** Eun Choi, Sun Ha Park, Kyung Mee Kim, Won Kee Lee, Sin Kam, Sung Ick Cha… in BMC Cancer (2007)

Article

Na⁺/H⁺exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells

The gene encoding Na⁺/H⁺ exchanger regulatory factor 1 (NHERF1) is a putative tumor suppressor gene that harbors frequent loss of heterozygosity (LOH) and intragenic mutations in breast carcinoma. The exact biolo...

Yong Pan, Edward J Weinman, Jia Le Dai in Breast Cancer Research (2008)

Article

Clinicopathologic significance of HIF-1α, p53, and VEGF expression and preoperative serum VEGF level in gastric cancer

Hypoxia influences tumor growth by inducing angiogenesis and genetic alterations. Hypoxia-inducible factor 1α (HIF-1α), p53, and vascular endothelial growth factor (VEGF) are all important factors in the mecha...

Sung Yong Oh, Hyuk-Chan Kwon, Sung-Hyun Kim, ** Seok Jang, Min Chan Kim… in BMC Cancer (2008)

Article

Activation of cytotoxic T lymphocytes against CML28-bearing tumors by dendritic cells transduced with a recombinant adeno-associated virus encoding the CML28 gene

Induction of anti-tumor immune responses by dendritic cells (DCs) transduced with a recombinant adeno-associated virus type 2 (rAAV2) encoding tumor antigens is considered a promising approach for cancer vacci...

Li-Hua **e, Fion Wan-Yee Sin, Samuel Chak-Sum Cheng… in Cancer Immunology, Immunotherapy (2008)

Article

Evaluation of high-risk Human papillomaviruses type distribution in cervical cancer in Sichuan province of China

Infection with high-risk human papillomavirus is an important factor associated with cervical cancer, and the distribution of HPV types varies greatly worldwide. Determination of type-specific HPV prevalence c...

En-qi Wu, Guo-nan Zhang, **ang-hui Yu, Yuan Ren, Ying Fan, Yong-ge Wu… in BMC Cancer (2008)

Article

Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cells

Cyclooxygenase (COX)-2 has been implicated in tumour progression, angiogenesis and metastasis in non-small cell lung cancer (NSCLC). We speculated that inhibition of COX-2 activity might reduce expression of t...

Yong Ming Zhu, Nor Saadah M Azahri, Danny CW Yu, Penella J Woll in BMC Cancer (2008)

Article

In silico analysis and verification of S100 gene expression in gastric cancer

The S100 protein family comprises 22 members whose protein sequences encompass at least one EF-hand Ca²⁺ binding motif. They were involved in the regulation of a number of cellular processes such as cell cycle pr...

Ji Liu, Xue Li, Guang-Long Dong, Hong-Wei Zhang, Dong-Li Chen, Jian-Jun Du… in BMC Cancer (2008)

Article

Prognostic significance of VEGF expression in patients with bulky cervical carcinoma undergoing neoadjuvant chemotherapy

The prediction of response to treatment would be valuable for managing cervical carcinoma with neoadjuvant chemotherapy.

Chel Hun Choi, Sang Yong Song, Jung-Joo Choi, Young Ae Park, Heeseok Kang… in BMC Cancer (2008)

Article

Prognostic parameters for recurrence of papillary thyroid microcarcinoma

Papillary thyroid microcarcinoma (PTMC) is defined as a papillary thyroid carcinoma less than or equal to 1.0 cm in size. Independent prognostic factors for clinical recurrence of PTMC have not been clearly de...

Tae Yong Kim, Suck Joon Hong, Jung Min Kim, Won Gu Kim, Gyungyub Gong… in BMC Cancer (2008)

Article

Voluntary exercise inhibits intestinal tumorigenesis in Apc ^Min/+mice and azoxymethane/dextran sulfate sodium-treated mice

Epidemiological studies suggest that physical activity reduces the risk of colon cancer in humans. Results from animal studies, however, are inconclusive. The present study investigated the effects of voluntar...

Jihyeung Ju, Bonnie Nolan, Michelle Cheh, Mousumi Bose, Yong Lin… in BMC Cancer (2008)