27 Result(s)

Article

Preclinical evaluation of [¹⁸F]FP-CIT, the radiotracer targeting dopamine transporter for diagnosing Parkinson’s disease: pharmacokinetic and efficacy analysis

N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (FP-CIT), the representative cocaine derivative used in dopamine transporter imaging, is a promising biomarker, as it reflects the severity of P.....

Jae Hun Ahn, Min Hwan Kim, Kyongkyu Lee, Keumrok Oh, Hyunwoo Lim… in EJNMMI Research (2024)

Article

Distinguishing thymic cysts from low-risk thymomas via [¹⁸F]FDG PET/CT

Thymic cysts are a rare benign disease that needs to be distinguished from low-risk thymoma. [¹⁸F]fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is a non-invasive imaging tec...

Sunju Choi, Yong-il Kim, Sangwon Han, Jae Kwang Yun, Geun Dong Lee… in EJNMMI Research (2024)

Article

Correction to: Clinical prospective study of Gallium 68 (68Ga)–labeled fibroblast‑activation protein inhibitor PET/CT in the diagnosis of biliary tract carcinoma

Li **ghua, Xu Kui, Guo Deliang, Liao Bo… in European Journal of Nuclear Medicine and M… (2023)

Article

Gut microbiota is associated with response to ¹³¹I therapy in patients with papillary thyroid carcinoma

Radioactive iodine (¹³¹I) therapy is a conventional post-surgery treatment widely used for papillary thyroid carcinoma (PTC). Since ¹³¹I is orally administered, we hypothesize that it may affect gut microbiome. T...

Lei Zheng, Lin**g Zhang, Li Tang… in European Journal of Nuclear Medicine and M… (2023)

Article

Deep learning and radiomics framework for PSMA-RADS classification of prostate cancer on PSMA PET

Accurate classification of sites of interest on prostate-specific membrane antigen (PSMA) positron emission tomography (PET) images is an important diagnostic requirement for the differentiation of prostate ca...

Kevin H. Leung, Steven P. Rowe, Jeffrey P. Leal, Saeed Ashrafinia… in EJNMMI Research (2022)

Article

First-in-human use of ¹¹C-CPPC with positron emission tomography for imaging the macrophage colony-stimulating factor 1 receptor

Study of the contribution of microglia to onset and course of several neuropsychiatric conditions is challenged by the fact that these resident immune cells often take on different phenotypes and functions out...

Jennifer M. Coughlin, Yong Du, Wojciech G. Lesniak… in EJNMMI Research (2022)

Article

Changes of regional cerebral blood flow after deep brain stimulation in cervical dystonia

Cervical dystonia is considered as a network disorder affecting various brain regions in recent days. Presumably, deep brain stimulation (DBS) of the internal segment of globus pallidus (GPi) may exert therape...

Sung** Park, Hyeonseok Jeong, Yong-An Chung, Ilhyang Kang, Seunghee Kim… in EJNMMI Research (2022)

Article

Radiosynthesis and characterization of [¹⁸F]BS224: a next-generation TSPO PET ligand insensitive to the rs6971 polymorphism

Translocator protein 18-kDa (TSPO) positron emission tomography (PET) is a valuable tool to detect neuroinflammed areas in a broad spectrum of neurodegenerative diseases. However, the clinical application of s...

Sang Hee Lee, Nunzio Denora… in European Journal of Nuclear Medicine and M… (2021)

Article

The impact of demographic, clinical, genetic, and imaging variables on tau PET status

A substantial proportion of amyloid-β (Aβ)+ patients with clinically diagnosed Alzheimer’s disease (AD) dementia and mild cognitive impairment (MCI) are tau PET–negative, while some clinically diagnosed non-AD...

Rik Ossenkoppele, Antoine Leuzy, Hanna Cho… in European Journal of Nuclear Medicine and M… (2021)

Article

Deep learning-based amyloid PET positivity classification model in the Alzheimer’s disease continuum by using 2-[¹⁸F]FDG PET

Considering the limited accessibility of amyloid position emission tomography (PET) in patients with dementia, we proposed a deep learning (DL)-based amyloid PET positivity classification model from PET images...

Suhong Kim, Peter Lee, Kyeong Taek Oh, Min Soo Byun, Dahyun Yi… in EJNMMI Research (2021)

Article

A three-stage, deep learning, ensemble approach for prognosis in patients with Parkinson’s disease

Diagnosis of Parkinson’s disease (PD) is informed by the presence of progressive motor and non-motor symptoms and by imaging dopamine transporter with [¹²³I]ioflupane (DaTscan). Deep learning and ensemble methods...

Kevin H. Leung, Steven P. Rowe, Martin G. Pomper, Yong Du in EJNMMI Research (2021)

Article

Automated detection and quantification of COVID-19 pneumonia: CT imaging analysis by a deep learning-based software

The novel coronavirus disease 2019 (COVID-19) is an emerging worldwide threat to public health. While chest computed tomography (CT) plays an indispensable role in its diagnosis, the quantification and localiz...

Hai-tao Zhang, **-song Zhang, Hai-hua Zhang… in European Journal of Nuclear Medicine and M… (2020)

Article

[¹⁸F]FDG uptake of bone marrow on PET/CT for predicting distant recurrence in breast cancer patients after surgical resection

The objective of this study was to investigate the prognostic value of 2-Deoxy-2-[¹⁸F]fluoro-D-glucose ([¹⁸F]FDG) uptake of bone marrow (BM) and metabolic parameters of primary tumor on positron emission tomograp...

Jeong Won Lee, Sung Yong Kim, Sun Wook Han, Jong Eun Lee, Hyun Ju Lee… in EJNMMI Research (2020)

Article

PET imaging of soluble epoxide hydrolase in non-human primate brain with [¹⁸F]FNDP

Soluble epoxide hydrolase (sEH) is a promising candidate positron emission tomography (PET) imaging biomarker altered in various disorders, including vascular cognitive impairment (VCI), Alzheimer’s disease (A...

Yong Du, Il Minn, Catherine Foss, Wojciech G. Lesniak, Feng Hu… in EJNMMI Research (2020)

Article

Tumour-to-liver ratio determined by [⁶⁸Ga]Ga-DOTA-TOC PET/CT as a prognostic factor of lanreotide efficacy for patients with well-differentiated gastroenteropancreatic-neuroendocrine tumours

Lanreotide is a long-acting somatostatin analogue with proven antitumour effects against well-differentiated (WD) gastroenteropancreatic-neuroendocrine tumours (GEP-NETs). However, there are no globally establ...

Yong-il Kim, Changhoon Yoo, Seung Jun Oh, Sang Ju Lee, Junho Kang… in EJNMMI Research (2020)

Article

The flow-metabolism ratio might predict treatment response and survival in patients with locally advanced esophageal squamous cell carcinoma

Perfusion CT can offer functional information about tumor angiogenesis, and ¹⁸F-FDG PET/CT quantifies the glucose metabolic activity of tumors. This prospective study aims to investigate the value of biologically...

Kewei Zhao, Chunsheng Wang, Qingfeng Mao, Dong** Shang, Yong Huang… in EJNMMI Research (2020)

Article

Interim analysis of the REASSURE (Radium-223 alpha Emitter Agent in non-intervention Safety Study in mCRPC popUlation for long-teRm Evaluation) study: patient characteristics and safety according to prior use of chemotherapy in routine clinical practice

REASSURE is a global, prospective, non-interventional study to assess long-term safety of radium-223 in patients with bone metastatic castration-resistant prostate cancer. Here we report an interim analysis of...

Sabina Dizdarevic, Peter Meidahl Petersen… in European Journal of Nuclear Medicine and M… (2019)

Article

Correction to: a risk stratification model for nodal peripheral T-cell lymphomas based on the NCCN-IPI and posttreatment Deauville score

Unfortunately, the original version of this article contained several errors made during final step of article production. In the results section (fourth sentence) of the Abstract, the incomplete sentence,”, 3...

Ho-Young Yhim, Yong Park, Yeon-Hee Han… in European Journal of Nuclear Medicine and M… (2018)

Article

Reply to ‘Single high dose versus repeated bone-targeted radionuclide therapy’

Ana M. Denis-Bacelar, Sarah J. Chittenden… in European Journal of Nuclear Medicine and M… (2018)

Article

Prognostic value of simultaneous ¹⁸F-FDG PET/MRI using a combination of metabolo-volumetric parameters and apparent diffusion coefficient in treated head and neck cancer

The aim of this study was to determine the usefulness of combined positron emission tomography (PET)/magnetic resonance imaging (MRI) parameters provided by simultaneous ¹⁸F-fluorodeoxyglucose (FDG) PET/MRI for t...

Yong-il Kim, Gi Jeong Cheon, Seo Young Kang, ** Chul Paeng… in EJNMMI Research (2018)