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  1. Article

    Open Access

    A dual tracer 68Ga-DOTANOC PET/CT and 18F-FDG PET/CT pilot study for detection of cardiac sarcoidosis

    Cardiac sarcoidosis (CS) is a potentially fatal condition lacking a single test with acceptable diagnostic accuracy. 18F-FDG PET/CT has emerged as a promising imaging modality, but is challenged by physiological ...

    Lars C. Gormsen, Ate Haraldsen, Stine Kramer, Andre H. Dias in EJNMMI Research (2016)

  2. Article

    Open Access

    Computational simulation of the predicted dosimetric impact of adjuvant yttrium-90 PET/CT-guided percutaneous ablation following radioembolization

    90Y PET/CT post-radioembolization imaging has demonstrated that the distribution of 90Y in a tumor can be non-uniform. Using computational modeling, we predicted the dosimetric impact ...

    Alexander S. Pasciak, Abigail Lin, Christos Georgiades in EJNMMI Research (2016)

  3. Article

    Open Access

    Tracking dendritic cell migration into lymph nodes by using a novel PET probe 18F-tetrafluoroborate for sodium/iodide symporter

    Recently, 18F-tetrafluoroborate (TFB) was used as a substrate for the human sodium/iodide symporter (hNIS) reporter gene. This study evaluated the feasibility of performing molecular-genetic imaging by using the ...

    Sang Bong Lee, Ho Won Lee, Hongje Lee, Yong Hyun Jeon, Sang-Woo Lee in EJNMMI Research (2017)

  4. Article

    Open Access

    Prognostic value of simultaneous 18F-FDG PET/MRI using a combination of metabolo-volumetric parameters and apparent diffusion coefficient in treated head and neck cancer

    The aim of this study was to determine the usefulness of combined positron emission tomography (PET)/magnetic resonance imaging (MRI) parameters provided by simultaneous 18F-fluorodeoxyglucose (FDG) PET/MRI for t...

    Yong-il Kim, Gi Jeong Cheon, Seo Young Kang, ** Chul Paeng in EJNMMI Research (2018)

  5. Article

    Open Access

    The flow-metabolism ratio might predict treatment response and survival in patients with locally advanced esophageal squamous cell carcinoma

    Perfusion CT can offer functional information about tumor angiogenesis, and 18F-FDG PET/CT quantifies the glucose metabolic activity of tumors. This prospective study aims to investigate the value of biologically...

    Kewei Zhao, Chunsheng Wang, Qingfeng Mao, Dong** Shang, Yong Huang in EJNMMI Research (2020)

  6. Article

    Open Access

    Tumour-to-liver ratio determined by [68Ga]Ga-DOTA-TOC PET/CT as a prognostic factor of lanreotide efficacy for patients with well-differentiated gastroenteropancreatic-neuroendocrine tumours

    Lanreotide is a long-acting somatostatin analogue with proven antitumour effects against well-differentiated (WD) gastroenteropancreatic-neuroendocrine tumours (GEP-NETs). However, there are no globally establ...

    Yong-il Kim, Changhoon Yoo, Seung Jun Oh, Sang Ju Lee, Junho Kang in EJNMMI Research (2020)

  7. Article

    Open Access

    PET imaging of soluble epoxide hydrolase in non-human primate brain with [18F]FNDP

    Soluble epoxide hydrolase (sEH) is a promising candidate positron emission tomography (PET) imaging biomarker altered in various disorders, including vascular cognitive impairment (VCI), Alzheimer’s disease (A...

    Yong Du, Il Minn, Catherine Foss, Wojciech G. Lesniak, Feng Hu in EJNMMI Research (2020)

  8. Article

    Open Access

    [18F]FDG uptake of bone marrow on PET/CT for predicting distant recurrence in breast cancer patients after surgical resection

    The objective of this study was to investigate the prognostic value of 2-Deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) uptake of bone marrow (BM) and metabolic parameters of primary tumor on positron emission tomograp...

    Jeong Won Lee, Sung Yong Kim, Sun Wook Han, Jong Eun Lee, Hyun Ju Lee in EJNMMI Research (2020)

  9. Article

    Open Access

    A three-stage, deep learning, ensemble approach for prognosis in patients with Parkinson’s disease

    Diagnosis of Parkinson’s disease (PD) is informed by the presence of progressive motor and non-motor symptoms and by imaging dopamine transporter with [123I]ioflupane (DaTscan). Deep learning and ensemble methods...

    Kevin H. Leung, Steven P. Rowe, Martin G. Pomper, Yong Du in EJNMMI Research (2021)

  10. Article

    Open Access

    Deep learning-based amyloid PET positivity classification model in the Alzheimer’s disease continuum by using 2-[18F]FDG PET

    Considering the limited accessibility of amyloid position emission tomography (PET) in patients with dementia, we proposed a deep learning (DL)-based amyloid PET positivity classification model from PET images...

    Suhong Kim, Peter Lee, Kyeong Taek Oh, Min Soo Byun, Dahyun Yi in EJNMMI Research (2021)

  11. Article

    Open Access

    Changes of regional cerebral blood flow after deep brain stimulation in cervical dystonia

    Cervical dystonia is considered as a network disorder affecting various brain regions in recent days. Presumably, deep brain stimulation (DBS) of the internal segment of globus pallidus (GPi) may exert therape...

    Sung** Park, Hyeonseok Jeong, Yong-An Chung, Ilhyang Kang, Seunghee Kim in EJNMMI Research (2022)

  12. Article

    Open Access

    First-in-human use of 11C-CPPC with positron emission tomography for imaging the macrophage colony-stimulating factor 1 receptor

    Study of the contribution of microglia to onset and course of several neuropsychiatric conditions is challenged by the fact that these resident immune cells often take on different phenotypes and functions out...

    Jennifer M. Coughlin, Yong Du, Wojciech G. Lesniak in EJNMMI Research (2022)

  13. Article

    Open Access

    Deep learning and radiomics framework for PSMA-RADS classification of prostate cancer on PSMA PET

    Accurate classification of sites of interest on prostate-specific membrane antigen (PSMA) positron emission tomography (PET) images is an important diagnostic requirement for the differentiation of prostate ca...

    Kevin H. Leung, Steven P. Rowe, Jeffrey P. Leal, Saeed Ashrafinia in EJNMMI Research (2022)

  14. Article

    Open Access

    Distinguishing thymic cysts from low-risk thymomas via [18F]FDG PET/CT

    Thymic cysts are a rare benign disease that needs to be distinguished from low-risk thymoma. [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is a non-invasive imaging tec...

    Sunju Choi, Yong-il Kim, Sangwon Han, Jae Kwang Yun, Geun Dong Lee in EJNMMI Research (2024)

  15. Article

    Open Access

    Preclinical evaluation of [18F]FP-CIT, the radiotracer targeting dopamine transporter for diagnosing Parkinson’s disease: pharmacokinetic and efficacy analysis

    N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (FP-CIT), the representative cocaine derivative used in dopamine transporter imaging, is a promising biomarker, as it reflects the severity of P.....

    Jae Hun Ahn, Min Hwan Kim, Kyongkyu Lee, Keumrok Oh, Hyunwoo Lim in EJNMMI Research (2024)