6,043 Result(s)
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Open AccessVoxelated bioprinting of modular double-network bio-ink droplets
Analogous of pixels to two-dimensional pictures, voxels—in the form of either small cubes or spheres—are the basic building blocks of three-dimensional objects. However, precise manipulation of viscoelastic bi...
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Open AccessAssessing long-term effects of gaseous air pollution exposure on mortality in the United States using a variant of difference-in-differences analysis
Long-term mortality effects of particulate air pollution have been investigated in a causal analytic frame, while causal evidence for associations with gaseous air pollutants remains extensively lacking, espec...
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Open AccessNitrifying niche in estuaries is expanded by the plastisphere
The estuarine plastisphere, a novel ecological habitat in the Anthropocene, has garnered global concerns. Recent geochemical evidence has pointed out its potential role in influencing nitrogen biogeochemistry....
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Open AccessLoss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression
Low response rate, treatment relapse, and resistance remain key challenges for cancer treatment with immune checkpoint blockade (ICB). Here we report that loss of specific tumor suppressors (TS) induces an inf...
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Open AccessAdeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade
There are numerous mechanisms by which glioblastoma cells evade immunological detection, underscoring the need for strategic combinatorial treatments to achieve appreciable therapeutic effects. However, develo...
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Open AccessWavelength-tunable high-fidelity entangled photon sources enabled by dual Stark effects
The construction of a large-scale quantum internet requires quantum repeaters containing multiple entangled photon sources with identical wavelengths. Semiconductor quantum dots can generate entangled photon p...
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Open AccessBetter performance of deep learning pulmonary nodule detection using chest radiography with pixel level labels in reference to computed tomography: data quality matters
Labeling errors can significantly impact the performance of deep learning models used for screening chest radiographs. The deep learning model for detecting pulmonary nodules is particularly vulnerable to such...
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Open AccessSilencing CK19 regulates ferroptosis by affecting the expression of GPX4 and ACSL4 in oral squamous cell carcinoma in vivo and in vitro
To analyze the mechanism of how interfering with the cytokeratin 19 (CK19) pathway via the ferroptosis pathway affects tumor biological behaviors in the process of oral squamous cell carcinoma (OSCC) developme...
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Open AccessTuning electronic structure of metal-free dual-site catalyst enables exclusive singlet oxygen production and in-situ utilization
Develo** eco-friendly catalysts for effective water purification with minimal oxidant use is imperative. Herein, we present a metal-free and nitrogen/fluorine dual-site catalyst, enhancing the selectivity an...
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Open AccessClassification of osteoarthritic and healthy cartilage using deep learning with Raman spectra
Raman spectroscopy is a rapid method for analysing the molecular composition of biological material. However, noise contamination in the spectral data necessitates careful pre-processing prior to analysis. Her...
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Open AccessGerm granule compartments coordinate specialized small RNA production
Germ granules are biomolecular condensates present in most animal germ cells. One function of germ granules is to help maintain germ cell totipotency by organizing mRNA regulatory machinery, including small RN...
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Open AccessMitigating drought-induced oxidative stress in wheat (Triticum aestivum L.) through foliar application of sulfhydryl thiourea
Drought stress is a major abiotic stress affecting the performance of wheat (Triticum aestivum L.). The current study evaluated the effects of drought on wheat phenology, physiology, and biochemistry; and assesse...
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Open AccessAuthor Correction: Welding-induced corrosion and protective measures for clad rebars in neutral chloride environments
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Open AccessMetabolic reprograming mediated by tumor cell-intrinsic type I IFN signaling is required for CD47-SIRPα blockade efficacy
Type I interferons have been well recognized for their roles in various types of immune cells during tumor immunotherapy. However, their direct effects on tumor cells are less understood. Oxidative phosphoryla...
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Open AccessAuthor Correction: Unravelling the spatial directionality of urban mobility
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Open AccessLOV1 protein of Pseudomonas cichorii JBC1 modulates its virulence and lifestyles in response to blue light
Bacteria perceive light signals via photoreceptors and modulate many physiological and genetic processes. The impacts played by light, oxygen, or voltage (LOV) and blue light (BL) photosensory proteins on the ...
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Open AccessMetagenomic comparison of intestinal microbiota between normal and liver fibrotic rhesus macaques (Macaca mulatta)
Liver fibrosis is an important pathological process in chronic liver disease and cirrhosis. Recent studies have found a close association between intestinal microbiota and the development of liver fibrosis. To...
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Open AccessHierarchically porous and single Zn atom-embedded carbon molecular sieves for H2 separations
Hierarchically porous materials containing sub-nm ultramicropores with molecular sieving abilities and microcavities with high gas diffusivity may realize energy-efficient membranes for gas separations. Howeve...
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Open AccessNational survey on the current status of airway management in China
Apparently, understanding airway management status may help to reduce risk and improve clinical practice. Given these facts, our team conducted a second survey on the current status of airway management for ma...
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Open AccessInvestigation on the molecular mechanism of SPA interference with osteogenic differentiation of bone marrow mesenchymal stem cells
Binding of Staphylococcus aureus protein A (SPA) to osteoblasts induces apoptosis and inhibits bone formation. Bone marrow-derived mesenchymal stem cells (BMSCs) have the ability to differentiate into bone, fa...