8,413 Result(s)
within
Yi**g Yong
Life Sciences
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Article
Effect of Chronic Kidney Disease on All-Cause Mortality After Hip Fracture Surgery: A Retrospective Cohort Study
In this retrospective cohort study, we investigated: (1) The impact of comorbid chronic kidney disease (CKD) on postoperative mortality in patients with a hip fracture; (2) mortality variations by dialysis typ...
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Beauveria bassiana (Ascomycota: Hypocreales) spores carried by Scleroderma guani (Hymenoptera: Bethylidae): a novel strategy for improving the control efficiency of Semanotus bifasciatus (Coleoptera: Cerambycidae) in the field
One common biocontrol strategy employed to combat the wood borer Semanotus bifasciatus Motschulsky (the Chinese fir borer, CFB) is the release of parasitic wasps, specifically Sclerodermus guani **ao et Wu. Howev...
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Seven decades of transformation: evaluating the dynamics of coral reef fish communities in the **sha Islands, South China Sea
The **sha Islands constitute the largest coral reef archipelago on the northern margin of the Coral Triangle and are the largest coral reef archipelago among the islands in the South China Sea. This study empl...
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Open AccessSynthetic macrolides overcoming MLSBK-resistant pathogens
Conventional macrolide-lincosamide-streptogramin B-ketolide (MLSBK) antibiotics are unable to counter the growing challenge of antibiotic resistance that is conferred by the constitutive methylation of rRNA base ...
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A genome-wide association study of panicle blast resistance to Magnaporthe oryzae in rice
Rice blast, caused by Magnaporthe oryzae (M. oryzae), is one of the most serious diseases worldwide. Develo** blast-resistant rice varieties is an effective strategy to control the spread of rice blast and redu...
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Permafrost conditions influence the abundance, distribution, and leaf traits of two closely related dominant shrub species (Rhododendron subsect. Ledum) in interior Alaska
Permafrost considerably influences boreal forest ecosystems by constraining the niche space of woody plants. The influence of permafrost on ecosystems could dramatically change with permafrost thawing due to r...
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Undibacterium cyanobacteriorum sp. nov., an auxin-producing bacterium isolated from fresh water during cyanobacterial bloom period
A novel Gram-negative, white-pigmented, and auxin-producing strain, 20NA77.5T, was isolated from fresh water during cyanobacterial bloom period. Pairwise comparison of the 16S rRNA gene sequences showed that stra...
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Open AccessIdentification of an H-Ras nanocluster disrupting peptide
Hyperactive Ras signalling is found in most cancers. Ras proteins are only active in membrane nanoclusters, which are therefore potential drug targets. We previously showed that the nanocluster scaffold galect...
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CD87-targeted BiTE and CAR-T cells potently inhibit invasive nonfunctional pituitary adenomas
Recently, bispecific T-cell engagers (BiTEs) and chimeric antigen receptor-modified T cells (CAR-Ts) have been shown to have high therapeutic efficacy in hematological tumors. CD87 is highly expressed in solid tu...
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Open AccessNew advances in drug development for metabolic dysfunction-associated diseases and alcohol-associated liver disease
Metabolic disorders are currently threatening public health worldwide. Discovering new targets and develo** promising drugs will reduce the global metabolic-related disease burden. Metabolic disorders primar...
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Tirzepatide alleviates oxidative stress and inflammation in diabetic nephropathy via IL-17 signaling pathway
Oxidative stress (OS) and inflammation play essential roles in the development of diabetic nephropathy (DN). Tirzepatide (TZP) has a protective effect in diabetes. However, its underlying mechanism in DN remai...
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Open AccessNon-O blood types are associated with a greater risk of large artery atherosclerosis stroke and dysregulation of cholesterol metabolism: an observational study
Previous research on ABO blood types and stroke has been controversial, predominantly suggesting heightened risk of stroke in non-O blood types. Nonetheless, investigations into the correlation and underlying ...
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Differential surface microbial community and thalli metabolome as early indicators of disease in red algae Pyropia yezoensis
To understand pathogenic mechanisms and suggest molecular biomarker candidates for the disease status of edible red algae, Pyropia, we analyzed relationships between disease symptom severity, changes in microbial...
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Article
Glycinamide Facilitates Nanocomplex Formation and Functions Synergistically with Bone Morphogenetic Protein 2 to Promote Osteoblast Differentiation In Vitro and Bone Regeneration in a Mouse Calvarial Defect Model
This study aimed to identify glycine analogs conducive to the formation of cell-absorbable nanocomplexes, enhancing collagen synthesis and subsequent osteogenesis in combination with BMP2 for improved bone reg...
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Open AccessProbiotic Lactobacillus rhamnosus GG improves insulin sensitivity and offspring survival via modulation of gut microbiota and serum metabolite in a sow model
Sows commonly experience insulin resistance in late gestation and lactation, causing lower feed intake and milk production, which can lead to higher mortality rates in newborn piglets. The probiotic Lactobacillus...
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Open AccessAcceleration of bone repairation by BMSCs overexpressing NGF combined with NSA and allograft bone scaffolds
Repairation of bone defects remains a major clinical problem. Constructing bone tissue engineering containing growth factors, stem cells, and material scaffolds to repair bone defects has recently become a hot...
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Structural elucidation a complex galactosyl and glucosyl-rich pectin from the pericarp of immature fruits of Juglans mandshurica Maxim.
A glucosyl-rich pectin, JMMP-3 (Mw, 2.572 × 104 g/mol, O-methyl % = 3.62%), was isolated and purified from the pericarp of the immature fruit of Juglans mandshurica Maxim. (QingLongYi). The structure of JMMP-3 wa...
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Transcriptome sequencing of the endangered land snail Karaftohelix adamsi from the Island Ulleung: De novo assembly, annotation, valuation of fitness genes and SSR markers
The Bradybaenidae snail Karaftohelix adamsi is endemic to Korea, with the species tracked from Island Ulleung in North Gyeongsang Province of South Korea. K. adamsi has been classified under the Endangered Wildli...
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In silico identification and expression analysis of superoxide dismutases in Tenebrio molitor
Insects encounter various environmental stresses, in response to which they generate reactive oxygen species (ROS). Superoxide dismutase (SOD) is an antioxidant metalloenzyme that scavenges superoxide radicals...
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Improvement of ventricular remodeling and regulation of PI3K/Akt/mTOR signaling pathway in rats with heart failure by polysaccharides from Stropharia rugosoannulata
Heart failure is a syndrome of impaired cardiac circulation caused by the inability of the heart to provide adequate blood supply.
