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    Article

    MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding

    The dynamic interaction between tumor cells and their microenvironment induces a proinflammatory milieu that drives cancer development and progression. The S100A8/A9 complex has been implicated in chronic infl...

    I. Made Winarsa Ruma, Endy Widya Putranto… in Clinical & Experimental Metastasis (2016)

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    Chapter

    Therapeutic Potential of Adenovirus Mediated Interleukin-12 Gene Therapy for Prostate Cancer

    Prostate cancer is characterized by extreme heterogeneity and multifocality of the primary tumour. The available clinical, pathological and molecular data suggest a lack of substantial clonal expansion at the ...

    Shin Ebara, Yasutomo Nasu, Takefumi Satoh… in Growth Factors and their Receptors in Canc… (2001)

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    Article

    Cooperative therapeutic effects of androgen ablation and adenovirus-mediated herpes simplex virus thymidine kinase gene and ganciclovir therapy in experimental prostate cancer

    Adenovirus-mediated transduction of the herpes simplex thymidine kinase gene (HSV-tk) in conjunction with ganciclovir (GCV) has been shown to result in significant growth suppression and to enhance survival in a ...

    Simon J Hall, Steven E Mutchnik, Guang Yang, Terry L Timme… in Cancer Gene Therapy (1999)

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    Article

    Suppression of caveolin expression induces androgen sensitivity in metastatic androgen-insensitive mouse prostate cancer cells

    Although prostate cancer cells are often initially sensitive to androgen ablation, they eventually lose this response and continue to survive, grow and spread in the absence of androgenic steroid...

    Yasutomo Nasu, Terry L. Timme, Guang Yang, Chris H. Bangma, Likun Li… in Nature Medicine (1998)