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Article
Open AccessEnhancing hepatoprotective action: oxyberberine amorphous solid dispersion system targeting TLR4
Oxyberberine (OBB) is a significant natural compound, with excellent hepatoprotective properties. However, the poor water solubility of OBB hinders its release and absorption thus resulting in low bioavailabil...
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Article
Author Correction: Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
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Article
Transcriptome Analysis Reveals Flower Development and the Role of Hormones in Three Flower Types of Grapevine
The molecular mechanism of flower development and sexual differentiation, which is an intricate process, still unclear in Vitis plants. In this study, we performed the transcriptome analysis by high-throughput se...
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Article
Feedback linearization control method for hydraulic flight simulation turntable based on variable inertia model compensation
The turntable plays an important role in semi-physical simulation of missiles and other aircraft. The precision of its control directly influences aircraft performance. However, the inertial coupling among the...
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Article
Open AccessPotential toxicity of graphene (oxide) quantum dots via directly covering the active site of anterior gradient homolog 2 protein
Graphene quantum dots (GQDs) have attracted significant attention in biomedicine, while extensive investigations have revealed a reverse regarding the potential biotoxicity of GQDs. In order to supplementing t...
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Article
Open AccessExtracellular vesicle therapy for obesity-induced NAFLD: a comprehensive review of current evidence
Non-alcoholic fatty liver disease (NAFLD) as a chronic disease especially in Western countries, is still a tough question in the clinical therapy. With the rising prevalence of various chronic diseases, liver ...
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Chapter and Conference Paper
Edge-Prior Contrastive Transformer for Optic Cup and Optic Disc Segmentation
Optic Cup and Optic Disc segmentation plays a vital role in retinal image analysis, with significant implications for automated diagnosis. In fundus images, due to the difference between intra-class features a...
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Chapter and Conference Paper
A Pressure-Bias-Modulated Aircraft Brake Control Algorithm with Runway Adaptation
The pressure-bias-modulated (PBM) is an aircraft antiskid brake algorithm with great engineering application. Its control structure is simple, with few debugging parameters, and it is reliable to prevent the w...
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Chapter and Conference Paper
Force-Position Hybrid Control of Motion Simulation Platform Based on Cable Drive
The cable driving motion simulation platform takes the cable as the driving link. Because of the unidirectional force of the cable, the traditional parallel control scheme is no longer applicable. In order to ...
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Chapter and Conference Paper
Configuration Optimization and Tension Distribution of Cable-Driven Motion Simulation Platform
Motion simulation platform is widely used to simulate the attitude and position changes of aircraft in space, but its motion space is often limited by the motion range of driving joint hydraulic cylinder or el...
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Article
Open AccessHigher systemic immune-inflammation index is associated with sarcopenia in individuals aged 18–59 years: a population-based study
The association between the systemic immune-inflammation index (SII) and the risk of sarcopenia has not yet been revealed. The purpose of this study was to investigate the relationship between the SII and sarc...
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Article
Clinic-radiomics model using liver magnetic resonance imaging helps predict chronicity of drug-induced liver injury
Some drug-induced liver injury (DILI) cases may become chronic, even after drug withdrawal. Radiomics can predict liver disease progression. We established and validated a predictive model incorporating the cl...
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Article
Label Propagation Based on Bipartite Graph
Label propagation (LP) is a popular graph-based semi-supervised learning framework. Its effectiveness is limited by the distribution of prior labels. If there are no objects with prior labels in parts of class...
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Article
Heavy Metals in Indoor Dust in China: Occurrence, Source, and Health Risk
Exposure to heavy metals in indoor dust may affect human health and has gained increasing attention in recent years. However, the occurrence, sources, and health risks of heavy metals in indoor dust in China a...
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Article
Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike
A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariant, BA.2.86, has emerged and spread to numerous countries worldwide, raising alarm because its spike protein contains 34 additiona...
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Article
Open AccessGraphene quantum dots blocking the channel egresses of cytochrome P450 enzyme (CYP3A4) reveals potential toxicity
Graphene quantum dots (GQDs) have garnered significant attention, particularly in the biomedical domain. However, extensive research reveals a dichotomy concerning the potential toxicity of GQDs, presenting co...
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Article
Open AccessMelanopsin-mediated optical entrainment regulates circadian rhythms in vertebrates
Melanopsin (OPN4) is a light-sensitive protein that plays a vital role in the regulation of circadian rhythms and other nonvisual functions. Current research on OPN4 has focused on mammals; more evidence is ne...
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Article
Programmable complex pum** field induced color-on-demand random lasing in fiber-integrated microbelts for speckle free imaging
Miniaturized lasers with on-demand color emission have immense potential in the development of integrated imaging sources. Random lasers (RLs) with cavity-free structures and low spatial coherence are promisin...
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Article
Comparison of the efficacy of autologous platelet gel and medical chitosan in the prevention of recurrence of intrauterine adhesions after transcervical resection of adhesion: a prospective, randomized, controlled trial
Intrauterine adhesion (IUAs) in women is a debatable topic and there is no clear consensus in its management and treatment strategies. Previous treatment measures have limitations which necessitates to conside...
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Article
Open AccessEucommia ulmoides polysaccharide modified nano-selenium effectively alleviated DSS-induced colitis through enhancing intestinal mucosal barrier function and antioxidant capacity
Ulcerative colitis (UC) is currently the most common inflammatory bowel disease (IBD). Due to its diverse and complex causes, there is no cure at present, and researchers are constantly exploring new therapies...
