688 Result(s)

Article

ASO Visual Abstract: Prognostic and Predictive Significance of Ki67 in Primary Nonmetastatic or Recurrent Acral Melanoma—Evidence from a Multicenter Retrospective Study

Chengcai Liang MD, PhD, Dandan Li MD, PhD, Yin Liang MD… in Annals of Surgical Oncology (2024)

Article

Analysis of tumor abnormal protein expression and epidermal growth factor receptor mutation status in non-small cell lung cancer

The level of tumor abnormal protein (TAP) level has a significant impact on tumor growth, recurrence, and metastasis. Previous studies have highlighted the influence of the mutations in exons 19 and 21 of the ...

Yuanjun Cheng, Bin Chen, Qianru Fang, Guohui Zang, Jie Yao in Discover Oncology (2024)

Article

Recursive partitioning analysis for survival stratification and early imaging prediction of molecular biomarker in glioma patients

Glioma is the most common primary brain tumor with high mortality and disability rates. Recent studies have highlighted the significant prognostic consequences of subty** molecular pathological markers using...

**an **e, Chen Luo, Shuai Wu, Wanyu Qiao, Wei Deng, Lei **, Junfeng Lu… in BMC Cancer (2024)

Article

Comparison of the diagnostic value of various microRNAs in blood for colorectal cancer: a systematic review and network meta-analysis

Despite the existence of numerous studies investigating the diagnostic potential of blood microRNAs for colorectal cancer, the microRNAs under consideration vary widely, and comparative analysis of their diagn...

Jianhao Xu, Lanfen Pan, Dan Wu, Liqian Yao, Wenqian Jiang, Jiarui Min… in BMC Cancer (2024)

Article

Diagnostic value of immune-related biomarker FAM83A in differentiating malignant from benign pleural effusion in lung adenocarcinoma

Malignant pleural effusion (MPE) is frequently observed in patients with advanced lung adenocarcinoma (LUAD). Pleural fluid cytology is a less invasive procedure compared to pleural biopsy. Therefore, it is cr...

Hangfeng Liu, Jia Yao, Yulan Liu, Li** Wu, Zhiwei Tan, Jie Hu… in Discover Oncology (2024)

Article

METTL3-induced circ_0008345 contributes to the progression of colorectal cancer via the microRNA-182-5p/CYP1A2 pathway

Circular RNA (circRNAs) have been found to play major roles in the progression of colorectal cancer (CRC). However, the functions of circ_0008345 (transcribed by PTK2) in regulating CRC development remain unde...

Chaofeng Hou, **bo Liu, Junwei Liu, Danjie Yao, Fang Liang, Congpeng Qin… in BMC Cancer (2024)

Article

Using machine learning to develop preoperative model for lymph node metastasis in patients with bladder urothelial carcinoma

Lymph node metastasis (LNM) is associated with worse prognosis in bladder urothelial carcinoma (BUC) patients. This study aimed to develop and validate machine learning (ML) models to preoperatively predict LN...

Junjie Ji, Tianwei Zhang, Ling Zhu, Yu Yao, **gchang Mei, Lijiang Sun… in BMC Cancer (2024)

Article

Pathomics and single-cell analysis of papillary thyroid carcinoma reveal the pro-metastatic influence of cancer-associated fibroblasts

Papillary thyroid carcinoma (PTC) is globally prevalent and associated with an increased risk of lymph node metastasis (LNM). The role of cancer-associated fibroblasts (CAFs) in PTC remains unclear.

Yixian Wang, **n Li, Qingwei Gang, Yinde Huang, Mingyu Liu, Han Zhang… in BMC Cancer (2024)

Article

Prognostic marker VPS72 could promote the malignant progression of prostate cancer

This paper attempted to clarify the role and mechanism of vacuolar protein sorting-associated protein 72 homolog (VPS72) in the progression of prostate cancer (PCa).

**aolong Xu, Wei Wang, Yi He, Yiqun Yao, Bo Yang in BMC Cancer (2024)

Article

Development and validation of an inflammatory biomarkers model to predict gastric cancer prognosis: a multi-center cohort study in China

Inflammatory factors have increasingly become a more cost-effective prognostic indicator for gastric cancer (GC). The goal of this study was to develop a prognostic score system for gastric cancer patients bas...

Shaobo Zhang, Hongxia Xu, Wei Li, Jiuwei Cui, Qingchuan Zhao, Zengqing Guo… in BMC Cancer (2024)

Article

Establishment of orthotopic osteosarcoma animal models in immunocompetent rats through muti-rounds of in-vivo selection

Immunodeficient murine models are usually used as the preclinical models of osteosarcoma. Such models do not effectively simulate the process of tumorigenesis and metastasis. Establishing a suitable animal mod...

Mengyu Yao, Zehua Lei, Feng Peng, Donghui Wang, Mei Li, Guoqing Zhong… in BMC Cancer (2024)

Article

Systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for lung cancer

Drug repurposing provides a cost-effective approach to address the need for lung cancer prevention and therapeutics. We aimed to identify actionable druggable targets using Mendelian randomization (MR).

Wenfu Song, Yingying Li, Yaxuan Yao, Shiling Sun, Xutao Guan, Bing Wang in BMC Cancer (2024)

Article

Neoadjuvant chemotherapy followed by surgery versus concurrent chemoradiotherapy in patients with stage IIB cervical squamous cell carcinoma: a retrospective cohort study

This study aims to compare treatment outcomes between neoadjuvant chemotherapy (NACT) followed by surgery and concurrent chemoradiotherapy (CCRT) in patients with stage IIB cervical squamous cell carcinoma (CS...

**n-Bin Pan, Yan Lu, You-Sheng Wei, De-Sheng Yao in BMC Cancer (2024)

Article

Protocol for CHAMPION study: a prospective study of maximal-cytoreductive therapies for patients with de novo metastatic hormone-sensitive prostate cancer who achieve oligopersistent metastases during systemic treatment with apalutamide plus androgen deprivation therapy

The proposed trial is to examine the feasibility of prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT)-guided cytoreduction plus apalutamide and androgen depriv...

Beihe Wang, Jian Pan, Tingwei Zhang, Xudong Ni, Yu Wei, **aomeng Li… in BMC Cancer (2024)

Article

A new prognostic model based on gamma-delta T cells for predicting the risk and aiding in the treatment of clear cell renal cell carcinoma

ccRCC is the prevailing form of RCC, accounting for the majority of cases. The formation of cancer and the body's ability to fight against tumors are strongly connected to Gamma delta (γδ) T cells.

Yaqian Wu, Mengfei Yao, Zonglong Wu, Lulin Ma, Cheng Liu in Discover Oncology (2024)

Article

Long non-coding RNA LINC00930 targeting miR-6792-3p/ZBTB16 regulates the proliferation and EMT of pancreatic cancer

Emerging evidence suggests the dysregulation of long non-coding RNAs (lncRNAs) involved in pancreatic cancer (PC). However, the function of LINC00930 in PC has not been elaborated. In this study, we found that...

Yingqing Mao, **an Su, Qingsong Guo, **hao Yao, Qun Zhao, Yibing Guo… in BMC Cancer (2024)

Article

A novel conditional survival nomogram for monitoring real-time prognosis of non-metastatic colorectal cancer

The aim of this study is to enhance the accuracy of monitoring and treatment information for patients diagnosed with colorectal cancer (CRC).

Pei Luo, Ying-ying Li, Can Huang, Jun Guo, **n Yao in Discover Oncology (2024)

Article

CA-125 elimination rate constant K (KELIM) as a promising predictor of complete cytoreduction after neoadjuvant chemotherapy in advanced ovarian cancer patients: a retrospective study from two Chinese hospitals

The modeled CA-125 elimination constant K (KELIM) is a potential marker of tumor chemosensitivity in ovarian cancer patients treated with neoadjuvant chemotherapy (NACT) before interval surgery. The objective ...

Cheng Li, Qiulin Cui, Xuanhui Wang, Shuzhong Yao, Hua Tu, Ming Chen in BMC Cancer (2024)