21 Result(s)
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Yanmei **n
Chemistry
Biotechnology
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Article
Open AccessSalicylic acid enhances cell growth, fatty acid and astaxanthin production in heterotrophic Chromochloris zofingiensis without reactive oxygen species elevation
The induction of lipid and astaxanthin accumulation in microalgae is often achieved through abiotic stress. However, this approach usually leads to oxidative stress, which results in relatively low growth rate...
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Open AccessCTSB Nuclear Translocation Facilitates DNA Damage and Lysosomal Stress to Promote Retinoblastoma Cell Death
Retinoblastoma (RB) is a pernicious tumor originating from photoreceptor precursor cells that often endangers the lives of children. The purpose of our study was to further investigate the influence of catheps...
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Open AccessCustomizing cancer treatment at the nanoscale: a focus on anaplastic thyroid cancer therapy
Anaplastic thyroid cancer (ATC) is a rare but highly aggressive kind of thyroid cancer. Various therapeutic methods have been considered for the treatment of ATC, but its prognosis remains poor. With the adven...
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Open AccessNanosilicate-functionalized nanofibrous membrane facilitated periodontal regeneration potential by harnessing periodontal ligament cell-mediated osteogenesis and immunomodulation
Although various new biomaterials have enriched the methods for periodontal regeneration, their efficacy is still controversial, and the regeneration of damaged support tissue in the periodontium remains chall...
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Biomanufacturing by In Vitro Biotransformation (ivBT) Using Purified Cascade Multi-enzymes
In vitro biotransformation (ivBT) refers to the use of an artificial biological reaction system that employs purified enzymes for the one-pot conversion of low-cost materials into biocommodities such as ethano...
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Open AccessMechanistic study of silica nanoparticles on the size-dependent retinal toxicity in vitro and in vivo
Silica nanoparticles (SiO2 NPs) are extensively applied in the biomedical field. The increasing medical application of SiO2 NPs has raised concerns about their safety. However, studies on SiO2 NP-induced retinal ...
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Open AccesspH-switchable nanozyme cascade catalysis: a strategy for spatial–temporal modulation of pathological wound microenvironment to rescue stalled healing in diabetic ulcer
The management of diabetic ulcer (DU) to rescue stalled wound healing remains a paramount clinical challenge due to the spatially and temporally coupled pathological wound microenvironment that features hyperg...
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Characterization on gut microbiome of PCOS rats and its further design by shifts in high-fat diet and dihydrotestosterone induction in PCOS rats
Polycystic ovary syndrome (PCOS) is associated with gut microbiota disturbance. Emerging evidence has shown that gut microbiota plays a major role in the development of PCOS. To better understand how the gut m...
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“One-step” characterization platform for pathogenic genetics of Staphylococcus aureus
Staphylococcus aureus (S. aureus) is an important human pathogen causing a variety of life-threatening diseases. In recent years, the health problem caused by S. aureus contaminated food has become a global healt...
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High-flux simultaneous screening of common foodborne pathogens and their virulent factors
Rapid and sensitive detection techniques for foodborne pathogens are important to the food industry. However, traditional detection methods rely on bacterial culture in combination with biochemical tests, a pr...
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Effects of phenothiazine and phenoxazine on photophysical properties of coumarin derivatives
Two new coumarin derivatives containing phenothiazine or phenoxazine moiety, 3-(benzo[d]oxazol-2-yl)-7-(10H-phenoxazin-10-yl)coumarin (PXZ-C) and 3-(benzo[d]oxazol-2-yl)-7-(10H-phenothiazin-10-yl)coumarin (PTZ-C)...
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Open AccessGREACE-assisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli
Late-stage fermentation broth contains high concentrations of target chemicals. Additionally, it contains various cellular metabolites which have leaked from lysed cells, which would exert multifactorial stres...
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Open AccessNitrogen and phosphorus removal from anaerobically digested wastewater by microalgae cultured in a novel membrane photobioreactor
With the further development of anaerobic digestion, an increasing output of anaerobically digested wastewater (ADW), which typically contained high concentrations of ammonium, phosphate, and suspended solids,...
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Open AccessDevelopment of a baculovirus vector carrying a small hairpin RNA for suppression of sf-caspase-1 expression and improvement of recombinant protein production
The Baculovirus expression vector system (BEVS) is a transient expression platform for recombinant protein production in insect cells. Baculovirus infection of insect cells will shutoff host translation and in...
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Identification of a Constitutively Active Mutant Mouse IRAK2 by Retroviral Expression Screening
To identify the importance of IRAK2 kinase activity in TLR-mediated signaling pathways, we constructed a retroviral vector harboring either a mouse IRAK2 gene (IRAK2-WT) or with its mutant with loss of functio...
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Open AccessImproved photobio-H2 production regulated by artificial miRNA targeting psbA in green microalga Chlamydomonas reinhardtii
Sulfur-deprived cultivation of Chlamydomonas reinhardtii, referred as “two-stage culture” transferring the cells from regular algal medium to sulfur-deplete one, has been extensively studied to improve photobio-H
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Article
The synthesis of a lanthanum metal–organic framework and its sensitivity electrochemical detection of H2O2
A lanthanum metal–organic framework, [La(BTC)(H2O)(DMF)] (H3BTC = 1, 3, 5-benzenetricarboxylic acid), was synthesized under mild hydrothermal conditions. The synthesized [La(BTC)(H2O)(DMF)] was characterized by s...
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Open AccessRole of Trichoderma reesei mitogen-activated protein kinases (MAPKs) in cellulase formation
Despite being the most important cellulase producer, the cellulase-regulating carbon source signal transduction processes in Trichoderma reesei are largely unknown. Elucidating these processes is the key for unve...
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Article
Combination of lithium chloride and pEGFP-N1-BmK CT effectively decreases proliferation and migration of C6 glioma cells
Deleterious invasiveness of glioma cells into the normal brain tissue is endorsed by its inherent ability to regulate the receptor-mediated adhesive properties, extracellular matrix degradation and remodeling ...
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Open AccessRapid and simple detection of methicillin-resistance staphylococcus aureus by orfXloop-mediated isothermal amplification assay
Methicillin-resistant Staphylococcus aureus (MRSA) has become one of the most prevalent pathogens responsible for nosocomial infections throughout the world. As clinical MRSA diagnosis is concerned, current diagn...
