1,243 Result(s)
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Yanmei **n
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Article
Open AccessPDX1+ cell budding morphogenesis in a stem cell-derived islet spheroid system
Remarkable advances in protocol development have been achieved to manufacture insulin-secreting islets from human pluripotent stem cells (hPSCs). Distinct from current approaches, we devised a tunable strategy...
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DLK1 regulates periodontal inflammation by inhibiting NF-κB p65 and JNK signaling pathways
The roles and molecular mechanisms of Delta-like 1 (DLK1) in periodontitis remain largely unknown. Here, we investigated the expression of DLK1 and NF-κB p65 in Porphyromonas gingivalis (Pg.)-induced periodontiti...
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Transcriptome analysis reveals the role of temperature in seed germination of Idesia polycarpa Maxim through the integration of phytohormones and sugar metabolism
The germination of Idesia polycarpa Maxim seeds plays a critical role in successfully cultivating this dioecious species. In order to reveal the mechanisms regulating the germination of I. polycarpa seeds under v...
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Efficacy and Safety of Corticosteroid in Combination with 5-Fluorouracil in the Treatment of Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis
Addressing hypertrophic scars and keloids poses a significant challenge in the realm of preventive and curative medicine. Combination corticosteroid with 5-fluorouracil (5-FU) is presumed to enhance the treatm...
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Open AccessABE-ultramax for high-efficiency biallelic adenine base editing in zebrafish
Advancements in CRISPR technology, particularly the development of base editors, revolutionize genetic variant research. When combined with model organisms like zebrafish, base editors significantly accelerate...
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Comparative analysis of the application with the combination of CMA and karyotype in routine and late amniocentesis
This is a retrospective comparative study. We aimed to analyze the results of karyotype and chromosomal microarray analysis (CMA) of amniotic fluid across different gestational weeks and evaluate the clinical ...
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Transcranial Direct Current Stimulation (tDCS) over the left dorsolateral prefrontal cortex reduced attentional bias toward natural emotional sounds
Previous research has indicated that the left dorsolateral prefrontal cortex (DLPFC) exerts an influence on attentional bias toward visual emotional information. However, it remains unclear whether the left DL...
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Drip irrigation under film mulch used on flat-bed increased vegetable yield by altering soil microbe community structure and soil nitrogen
The leafy vegetable production is challenged by the excessive water and fertilizer input, as well as the continuous crop** obstacle caused by the soil environment change. The different combinations of irriga...
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Multi-plug Filtration Purification Combined with High-Performance Liquid Chromatography-Tandem Mass Spectrometry for the Simultaneous Determination of Pesticides, Veterinary Drugs, Mycotoxins, and Persistent Organic Pollutants in Livestock and Poultry Meat
A method for the determination of 106 pesticides, 74 veterinary drugs, 10 mycotoxins, and 18 persistent organic pollutants in livestock and poultry meat was developed and validated in the present study. The me...
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Approximate moment dynamic of stochastic resonance facilitating bistable energy harvesting systems
Stochastic resonance, as a counterintuitive effect between weak coherent signal and noise in certain circumstance, has attracted wide attention from energy harvesting design. In this paper, our aim is to exami...
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Open AccessSerum lipid metabolism characteristics and potential biomarkers in patients with unilateral sudden sensorineural hearing loss
Glycerophospholipids (GPLs) are essential for cell membrane structure and function. Sphingomyelin and its metabolites regulate cell growth, apoptosis, and stress responses. This study aimed to investigate lipi...
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Spacing-adjustable and switchable multi-wavelength erbium-doped fiber laser using the filter of MMF–PMF–MMF based on PHB
A spacing-adjustable and switchable multi-wavelength erbium-doped fiber laser is proposed and analyzed based on the polarization hole burning (PHB) effect. The comb filter consists of multimode fiber–polarizat...
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Open AccessGenome-wide development of simple sequence repeats markers and genetic diversity analysis of chayote
Chayote is a high economic crop in the Cucurbitaceae family, playing an important role in food production, disease treatment and the production of degradable materials in industries. Due to the harsh environme...
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Open AccessPretreatment with or without GnRH-agonist before frozen–thawed embryo transfer in patients with PCOS: a systematic review and meta-analysis
This study was aimed to systematically evaluate the efficacy of artificial cycle-prepared frozen–thawed embryo transfer (FET) with or without gonadotrophin-releasing hormone agonist (GnRH-a) pretreatment for w...
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hsa_circ_0002454 controls cervical cancer cell growth and metastasis by targeting SDC4 through miR-654-3p
Circular RNAs (circRNAs) are involved in tumor growth and metastasis. The aim of this study was to elucidate the possible role of has_circ_0002454 in cervical cancer (CC) and its potential molecular mechanism.
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Open AccessAnnual dynamics of global remote industrial heat sources dataset from 2012 to 2021
The spatiotemporal distribution of industrial heat sources (IHS) is an important indicator for assessing levels of energy consumption and air pollution. Continuous, comprehensive, dynamic monitoring and public...
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Open AccessIdentification of genetic variants controlling diosgenin content in Dioscorea zingiberensis tuber by genome-wide association study
Diosgenin is an important steroidal precursor renowned for its diverse medicinal uses. It is predominantly sourced from Dioscorea species, particularly Dioscorea zingiberensis. Dioscorea zingiberensis has an abil...
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Open AccessGenome-wide association analysis and transgenic characterization for amylose content regulating gene in tuber of Dioscorea zingiberensis
Amylose, a prebiotic found in yams is known to be beneficial for the gut microflora and is particularly advantageous for diabetic patients’ diet. However, the genetic machinery underlying amylose production re...
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A Novel Effect of Id2 in Microglia TNFα Regulation
Microglia are the most important immune cells in the central nervous system (CNS), which can defend against external pathogens and stimuli. Dysregulation of microglia releases excessive proinflammatory cytokin...
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Air pollution, greenspace exposure and risk of Parkinson's disease: a prospective study of 441,462 participants
The current understandings of the relationship between air pollution (AP), greenspace exposure and Parkinson's Disease (PD) remain inconclusive.
