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    Article

    FSCN1 induced PTPRF-dependent tumor microenvironment inflammatory reprogramming promotes lung adenocarcinoma progression via regulating macrophagic glycolysis

    Macrophages (MΦs) play a dual role in the promotion and suppression of lung adenocarcinoma (LUAD), the function of which is influenced by the metabolic status. The role of protein tyrosine phosphatase receptor...

    Yiwei Huang, Guangyao Shan, Yanjun Yi, Jiaqi Liang, Zhengyang Hu in Cellular Oncology (2022)

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    Open Access

    IL6-STAT3-C/EBPβ-IL6 positive feedback loop in tumor-associated macrophages promotes the EMT and metastasis of lung adenocarcinoma

    Lung cancer is one of the most common tumors in the world, and metastasis is one of the major causes of tumor-related death in lung cancer patients. Tumor-associated macrophages (TAMs) are a major component of...

    Zhengyang Hu, Qihai Sui, **ng ** in Journal of Experimental & Clinical Cancer … (2024)