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Downregulation of miR-133 via MAPK/ERK signaling pathway involved in nicotine-induced cardiomyocyte apoptosis

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  1. Article

    Open Access

    Isoprenaline/β2-AR activates Plexin-A1/VEGFR2 signals via VEGF secretion in gastric cancer cells to promote tumor angiogenesis

    The role of stress signals in regulating gastric cancer initiation and progression is not quite clear. It is known that stress signals modulate multiple processes such as immune function, cell migration and an...

    Yanjie Lu, Qian Xu, Yanzhen Zuo, Lei Liu, Shaochen Liu, Lei Chen, Kang Wang in BMC Cancer (2017)

  2. Article

    Open Access

    Upregulation of M3 muscarinic receptor inhibits cardiac hypertrophy induced by angiotensin II

    M3 muscarinic acetylcholine receptor (M3-mAChR) is stably expressed in the myocardium, but its pathophysiological role remains largely undefined. This study aimed to investigate the role of M3-mAChR in cardiac hy...

    Yan Liu, Shu Wang, Chao Wang, Haoxin Song, Hongmei Han in Journal of Translational Medicine (2013)

  3. Article

    Correction: Corrigendum: The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

    Nat. Med. 13, 486–497 (2007); published online 1 April 2007; corrected after print 6 December 2011 In the version of this article initially published, lanes from the original blot shown in Figure 2b (NIZ and I...

    Baofeng Yang, Huixian Lin, Jiening **ao, Yanjie Lu, **aobin Luo in Nature Medicine (2011)

  4. Article

    Addendum: The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

    Baofeng Yang, Huixian Lin, Jiening **ao, Yanjie Lu, **aobin Luo in Nature Medicine (2011)

  5. Article

    Open Access

    Overexpression of M3 Muscarinic Receptor Is a Novel Strategy for Preventing Sudden Cardiac Death in Transgenic Mice

    The present study was designed to investigate the cardiac benefits of M3 muscarinic receptor (M3-mAChR) overexpression and whether these effects are related to the regulation of the inward rectifying K+ channel b...

    Yan Liu, Lihua Sun, Zhenwei Pan, Yunlong Bai, Ning Wang, **long Zhao in Molecular Medicine (2011)

  6. Article

    Open Access

    miRNAs at the heart of the matter

    Cardiovascular disease is among the main causes of morbidity and mortality in developed countries. The pathological process of the heart is associated with altered expression profile of genes that are importan...

    Zhiguo Wang, **oabin Luo, Yanjie Lu, Baofeng Yang in Journal of Molecular Medicine (2008)