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    Open Access

    MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment

    Programmed death-1 (PD-1) immune checkpoint blockade has achieved clinical successes in cancer therapy. However, the response rate of anti-PD-1 agents remains low. Additionally, a subpopulation of patients dev...

    Douglas D. Fang, Qiuqiong Tang, Yanhui Kong… in Journal for ImmunoTherapy of Cancer (2019)

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