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GADD45α alleviates acetaminophen-induced hepatotoxicity by promoting AMPK activation

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  1. Article

    Open Access

    Cellular metabolism regulates the differentiation and function of T-cell subsets

    T cells are an important component of adaptive immunity and protect the host from infectious diseases and cancers. However, uncontrolled T cell immunity may cause autoimmune disorders. In both situations, anti...

    Sicong Ma, Yanan Ming, **gxia Wu, Guoliang Cui in Cellular & Molecular Immunology (2024)

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  2. Article

    Open Access

    The malate shuttle detoxifies ammonia in exhausted T cells by producing 2-ketoglutarate

    The malate shuttle is traditionally understood to maintain NAD+/NADH balance between the cytosol and mitochondria. Whether the malate shuttle has additional functions is unclear. Here we show that chronic viral i...

    Nina Weisshaar, Sicong Ma, Yanan Ming, Alaa Madi, Alessa Mieg… in Nature Immunology (2023)

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