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Article
Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening
Icariin (ICA) has a good neuroprotective effect and can upregulate neuronal basal autophagy in naturally aging rats. Mitochondrial dysfunction is associated with brain aging-related neurodegenerative diseases....
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Article
Open AccessCorrection: A cross-sectional study: family communication, anxiety, and depression in adolescents: the mediating role of family violence and problematic internet use
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Open AccessA cross-sectional study: family communication, anxiety, and depression in adolescents: the mediating role of family violence and problematic internet use
The objective of this study is to explore the relationship between family communication, family violence, problematic internet use, anxiety, and depression and validate their potential mediating role.
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Article
Open AccessPrognostic factors in colorectal liver metastases patients with various tumor numbers treated by liver resection: a single-center, retrospective study
Multiple liver metastases is considered a risk factor for overall survival of colorectal liver metastases patients (CRLM) after curative resection. However, whether the prognostic factors were constant in pati...
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Article
Perioperative second-line chemotherapy is beneficial for resectable liver metastases that occur during or early after adjuvant chemotherapy for colorectal cancer
The prognosis of patients with liver metastases during or early after adjuvant chemotherapy for colorectal cancer (CRC) is significantly worse. This study aimed to explore the efficacy of perioperative second-...
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Preoperative CA19-9: a competitive predictor of recurrence in patients with colorectal cancer liver metastases after hepatectomy
The role of preoperative carbohydrate antigen 19-9 (CA19-9) in colorectal cancer liver metastases (CRLM) patients is still unclear. The present study aimed to explore the prognostic significance of preoperativ...
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Article
Open AccessLow calf circumference is associated with frailty in diabetic adults aged over 80 years
Frailty is now seen as a significant factor in older people with diabetes, whose mortality and disability increased. This study aims to investigate the association between calf circumference (CC) with frailty ...
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Open AccessPredictive value of prenatal ultrasound parameters for dichorionic growth discordant twins
Twin growth discordance was demonstrated to be a risk factor for adverse perinatal outcomes, and prenatal ultrasonographic methods were utilized to predict twin growth discordance to improve outcomes. The resu...
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Article
Comparison of the efficacy of Nutritional Risk Screening 2002 and Mini Nutritional Assessment Short Form in recognizing sarcopenia and predicting its mortality
This study aimed to examine the efficacy of Nutritional Risk Screening 2002 (NRS2002) and Mini Nutritional Assessment Short Form (MNA-SF) in recognizing sarcopenia and predicting its mortality in Chinese geria...
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Article
Advanced Studies on Rhizoma Dioscoreae Collettii
Rhizoma Dioscoreae Collettii, is known as Huang Dioscorea collettii, Rhizoma Coptidis Brevisepalae or yellow ginger. It is neutral in nature and bitter in taste which is described to Gan (Liver) meridian, Wei (St...
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Article
Intermediate-stage HCC—upfront resection can be feasible
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Open AccessAn epidemiological investigation of leukemia incidence between 2003 and 2007 in Nan**g, China
There has been little literature about leukemia epidemiology in Nan**g in recent years. We aimed to explore the incidence rate, gender and age distribution of leukemia in Nan**g using the leukemia database o...
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Article
The R229Q mutation in NPHS2 may predispose to proteinuria in thin-basement-membrane nephropathy
Thin-basement-membrane nephropathy (TBMN) is characterized by persistent dysmorphic hematuria, and the presence of proteinuria is a risk factor for renal impairment. TBMN is often due to mutations in the COL4A3 a...
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Article
Nine novel COL4A3 and COL4A4 mutations and polymorphisms identified in inherited membrane diseases
Both thin basement membrane nephropathy (TBMN) and autosomal recessive Alport syndrome result from mutations in the COL4A3 and COL4A4 genes, and this study documents further mutations and polymorphisms in these g...
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Article
Do mutations in COL4A1 or COL4A2 cause thin basement membrane nephropathy (TBMN)?
Thin basement membrane nephropathy (TBMN) is the commonest cause of persistent glomerular haematuria and often presents in childhood. Only 40% of affected individuals have mutations identified in the COL4A3 and C...
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Persistent familial hematuria in children and the locus for thin basement membrane nephropathy
This study examined how often children with persistent familial hematuria were from families where hematuria segregated with the known genetic locus for the condition known as benign familial hematuria or thin...