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SRP54 Negatively Regulates IFN-Beta Production and Antiviral Response by Targeting RIG-I and MDA5

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  1. Article

    Open Access

    SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response

    A novel SARS-related coronavirus (SARS-CoV-2) has recently emerged as a serious pathogen that causes high morbidity and substantial mortality. However, the mechanisms by which SARS-CoV-2 evades host immunity r...

    Yu-Zhi Fu, Su-Yun Wang, Zhou-Qin Zheng, Yi Huang in Cellular & Molecular Immunology (2021)

  2. Article

    Open Access

    The Regulation of cGAS

    The cGAS-MITA pathway of cytosolic DNA sensing plays essential roles in immune response against pathogens that contain DNA or with DNA production in their life cycles. The cGAS-MITA pathway also detects leaked...

    Meiguang **ong, Suyun Wang, Yan-Yi Wang, Yong Ran in Virologica Sinica (2018)