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    Article

    DL-3-n-butylphthalide ameliorates diabetes-associated cognitive decline by enhancing PI3K/Akt signaling and suppressing oxidative stress

    DL-3-n-Butylphthalide (DL-NBP), a small molecular compound extracted from the seeds of Apium graveolens Linn (Chinese celery), has been shown to exert neuroprotective effects due to its anti-inflammatory, anti-ox...

    Bei-ni Wang, Cheng-biao Wu, Zi-miao Chen, Pei-pei Zheng in Acta Pharmacologica Sinica (2021)

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    Article

    Metformin promotes microglial cells to facilitate myelin debris clearance and accelerate nerve repairment after spinal cord injury

    Spinal cord injury (SCI) is one kind of severe trauma for central nervous system. Myelin debris clearance and axon regeneration are essential for nerve regeneration after SCI. Metformin, a glucose-lowering dru...

    Yan-qing Wu, Jun **ong, Zi-li He, Yuan Yuan, Bei-ni Wang in Acta Pharmacologica Sinica (2022)