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2,087 Result(s)
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Article
Open AccessChromosome-level Genome Assembly of Theretra japonica (Lepidoptera: Sphingidae)
Theretra japonica is an important pollinator and agricultural pest in the family Sphingidae with a wide range of host plants. High-quality genomic resources facilitate investigations into behavioral ecology, morp...
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Breast lesions on MRI in mass and non-mass enhancement: Kaiser score and modified Kaiser score + for readers of variable experience
To compare the diagnostic performance of three readers using BI-RADS and Kaiser score (KS) based on mass and non-mass enhancement (NME) lesions.
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Inorganic and organic nutrients in tropical–subtropical Western Pacific coral reef waters
Coral reef ecosystems host diversified and highly productive communities, but corals are degrading in many places worldwide. Picking suitable locations to maximize coral conservation and restoration efforts is...
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Open AccessReformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation
Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this. Here, we reformu...
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Open AccessPhase separation of RNF214 promotes the progression of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors, and the expression and function of an uncharacterized protein RNF214 in HCC are still unknown. Phase separation has recently been obse...
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Cancer cell extravasation requires iplectin-mediated delivery of MT1-MMP at invadopodia
Invadopodia facilitate cancer cell extravasation, but the molecular mechanism whereby invadopodia-specific proteases such as MT1-MMP are called to invadopodia is unclear.
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Open AccessGenome-wide association study for cashmere traits in Inner Mongolia cashmere goat population reveals new candidate genes and haplotypes
The cashmere goat industry is one of the main pillars of animal husbandry in Inner Mongolia Autonomous Region, and plays an irreplaceable role in local economic development. With the change in feeding methods ...
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Open AccessRapid detection of lung cancer based on serum Raman spectroscopy and a support vector machine: a case-control study
Early screening and detection of lung cancer is essential for the diagnosis and prognosis of the disease. In this paper, we investigated the feasibility of serum Raman spectroscopy for rapid lung cancer screen...
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Point cloud-based model-free path planning method of robotic grinding for large complex forged parts
Large and complex forgings, serving as key load-supporting components in the fields of energy, ships, transportation, etc., require high dimensional accuracy and surface quality during post-processing. The aut...
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Article
PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury
Synchronized ferroptosis contributes to nephron loss in acute kidney injury (AKI). However, the propagation signals and the underlying mechanisms of the synchronized ferroptosis for renal tubular injury remain...
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Gliclazide Ameliorates Neuronal Injury by Attenuating Oxidative Stress in D-gal-Induced Senescent Cells and Aging Mice
Enhancement of oxidative stress and resultant neuronal injury play important roles in initiating cognitive impairment during the aging process. Thus, attenuating oxidative injury is regarded as a profitable th...
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Research on Hepatocyte Regulation of PCSK9-LDLR and Its Related Drug Targets
The prevalence of hyperlipidemia has increased significantly due to genetic, dietary, nutritional and pharmacological factors, and has become one of the most common pathological conditions in humans. Hyperlipi...
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Article
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway
Parkin (PARK2) deficiency is frequently observed in various cancers and potentially promotes tumor progression. Here, we showed that Parkin expression is downregulated in liver cancer tissues, which correlates wi...
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UPLC-Q-TOF/MS-Based Serum Metabolomics Reveals Potential Anti-tumor Mechanism of Banxia **exin Decoction in Colorectal Cancer Mice
To clarify the potential mechanism of Banxia **exin Decoction (BXD) on colorectal cancer (CRC) from the perspective of metabolomics.
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Open AccessMeasurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...
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Open AccessIntraoperative urinary tract resection and construction in CRS + HIPEC procedures: a single center retrospective analysis
The safety and efficacy of CRS + HIPEC combined with urinary tract resection and reconstruction are controversial. This study aims to summarize the clinicopathological features and to evaluate the safety and s...
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Article
Regioselective epitaxial growth of metallic heterostructures
Constructing regioselective architectures in heterostructures is important for many applications; however, the targeted design of regioselective architectures is challenging due to the sophisticated processes,...
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An universal in-situ phosphating strategy to fabricate high-performance Co2P-based bifunctional oxygen electrocatalyst derived from conjugated polyaniline-phytic acid copolymer
Electrocatalysts play a crucial role in the performance of rechargeable Zn-air batteries (ZABs), but it is still difficult to produce nonprecious materials with excellent bifunctional oxygen reduction reaction...
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Open AccessCold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy
Recently, environmental temperature has been shown to regulate bone homeostasis. However, the mechanisms by which cold exposure affects bone mass remain unclear. In our present study, we observed that exposure...
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Article
MHGNN: Multi-view fusion based Heterogeneous Graph Neural Network
Heterogeneous Graph (HG) is a data structure composed of various types of nodes and rich relational information, which can accurately show complex application scenarios in the real world. Although heterogeneou...