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  1. No Access

    Article

    Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR

    The dorsal hippocampus is involved in behavioral avoidance regulation. It is unclear how experiences such as the neonatal stress of maternal deprivation (MD) and post-weaning environmental enrichment (EE) affe...

    Fengmei Wei, **ao Deng, Bo Ma, Wenhao Li, Yajie Chen… in Cellular and Molecular Neurobiology (2023)

  2. Article

    Open Access

    Dual regulation of p53 by the ribosome maturation factor SBDS

    The Shwachman-Bodian Diamond syndrome (SBDS)-associated gene, SBDS, is involved in rRNA synthesis and ribosome maturation, but the role of SBDS in cancer is largely elusive. In this study, we found that SBDS is o...

    Qian Hao, Jieqiong Wang, Yajie Chen, Shanshan Wang, Mingming Cao… in Cell Death & Disease (2020)

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  3. Article

    Open Access

    Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53

    Hotspot p53 mutants augment cancer cell proliferation, metastasis and metabolism through their gain-of-function (GOF). Ovarian cancer sustains the highest frequency of TP53 mutations, but the mechanisms underlyin...

    Yajie Chen, Qian Hao, Jieqiong Wang, Jiajia Li, Canhua Huang… in Cell Death & Disease (2019)

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