-
Article
Effectiveness and safety of orelabrutinib with rituximab and lenalidomide in low KPS score and elderly patients with newly diagnosed primary central nervous system lymphoma—a single-center retrospective study
-
Article
IRE1α: from the function to the potential therapeutic target in atherosclerosis
Inositol requiring enzyme 1 (IRE1) is generally thought to control the most conserved pathway in the unfolded protein response (UPR). Two isoforms of IRE1, IRE1α and IRE1β, have been reported in mammals. IRE1α...
-
Article
Nitrogen-rich hollow carbon microspheres with tunable shell thicknesses for enhanced CO2 adsorption
Nitrogen-rich hollow carbon microspheres were successfully synthesized using resorcinol and formaldehyde as carbon sources, tetraethylenepentamine (TEPA) as a catalyst, and nitrogen source, with SiO2 microsphe...
-
Article
Open AccessArtemisinin ameliorates cognitive decline by inhibiting hippocampal neuronal ferroptosis via Nrf2 activation in T2DM mice
Neuronal ferroptosis plays a critical role in the pathogenesis of cognitive deficits. The present study explored whether artemisinin protected type 2 diabetes mellitus (T2DM) mice from cognitive impairments by...
-
Article
Open AccessComprehensive analyses of solute carrier family members identify SLC12A2 as a novel therapy target for colorectal cancer
As the largest transporter family impacting on tumor genesis and development, the prognostic value of solute carrier (SLC) members has not been elucidated in colorectal cancer (CRC). We aimed to identify a pro...
-
Article
Open AccessCharacterization of Firmiana danxiaensis plastomes and comparative analysis of Firmiana: insight into its phylogeny and evolution
Firmiana danxiaensis is a critically endangered and ecologically important tree currently only found in four locations in Danxia or Karst habitats in northern Guangdong Province, China. The specialized habitat pr...
-
Article
Expression of mitochondrial transcription factor A in granulosa cells: implications for oocyte maturation and in vitro fertilization outcomes
In vitro fertilization-embryo transfer (IVF-ET) is a widely used treatment for infertility, with oocyte maturation and quality having a significant impact on oocyte fertilization, embryo development, and fetal...
-
Article
Optimization of the microstructure, mechanical properties, and wear resistance of nacre-inspired TiB2/Al-Cu composites via gelatin addition
Nacre-inspired TiB2/Al-Cu composites were prepared by freeze casting and squeeze casting. This study focused on the effect of gelatin content on microstructure, mechanical characteristics, and wear resistance of ...
-
Article
A novel monospecific tetravalent IgG1-(scFv)2 version shown enhanced neutralizing and Fc-mediated effector functions against SARS-CoV-2
Neutralizing monoclonal antibodies (nMABs) have been proved to be effective therapeutics in treating coronavirus disease (COVID-19). To enhance the potency of nMAB 553–15, we generated a novel monospecific tet...
-
Article
Lithiophilic montmorillonite as a robust substrate toward high-stable lithium metal anodes
-
Article
The effect of discontinuation of maintenance therapy in Chinese patients with MPO-ANCA associated vasculitis who were in long-term stable remission
There is a consensus that maintenance therapy should be used to prevent relapse of myeloperoxidase-anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (MPO-AAV), but there is a debate about the o...
-
Article
4-OI ameliorates bleomycin-induced pulmonary fibrosis by activating Nrf2 and suppressing macrophage-mediated epithelial-mesenchymal transition
Pulmonary fibrosis (PF) is a chronic and refractory interstitial lung disease with limited therapeutic options. 4-octyl itaconate (4-OI), a cell-permeable derivative of itaconate, has been shown to have anti-o...
-
Article
The mechanisms of rapid seed germination in Caragana species adapted to low mean annual precipitation
The rapid seed germination of Caragana species adapted to arid environments is closely related to their high seed coat permeability, mist absorption, high GA promotion, and reduced ABA inhibition.
-
Article
Homogenization for polynomial optimization with unbounded sets
This paper considers polynomial optimization with unbounded sets. We give a homogenization formulation and propose a hierarchy of Moment-SOS relaxations to solve it. Under the assumptions that the feasible set...
-
Article
Open AccessEffects of dietary supplementation with a carvacrol–cinnamaldehyde–thymol blend on growth performance and intestinal health of nursery pigs
Stress, herd transfer, and food changes experienced by nursery and fattening pigs can lead to reduced performance, reduced digestion and absorption, and impaired intestinal health. Given the role of essential ...
-
Article
Open AccessRetraction Note: Mutagenesis combined with fermentation optimization to enhance gibberellic acid GA3 yield in Fusarium fujikuroi
-
Article
Generalized Truncated Moment Problems with Unbounded Sets
This paper studies generalized truncated moment problems with unbounded sets. First, we study geometric properties of the truncated moment cone and its dual cone of nonnegative polynomials. By the technique of...
-
Article
Open AccessRETRACTED ARTICLE: Mutagenesis combined with fermentation optimization to enhance gibberellic acid GA3 yield in Fusarium fujikuroi
Gibberellic acid (GA3) is a plant growth hormone that plays an important role in the production of crops, fruits, and vegetables with a wide market share. Due to intrinsic advantages, liquid fermentation of Fusar...
-
Article
Open AccessFirst commissioning results of the coherent scattering and imaging endstation at the Shanghai soft X-ray free-electron laser facility
The Shanghai soft X-ray free-electron laser (SXFEL) user facility project started in 2016 and is expected to be open to users by 2022. It aims to deliver ultra-intense coherent femtosecond X-ray pulses to five...
-
Article
Clinical features and outcomes of anti-neutrophil cytoplasmic autoantibody-associated vasculitis in Chinese childhood-onset patients
Data on anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) are limited in children. This study is to determine the clinical features and outcomes of childhood-onset AAV. A retrospective study was...
