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Open AccessProduction of enterodiol from defatted flaxseeds through biotransformation by human intestinal bacteria
The effects of enterolignans, e.g., enterodiol (END) and particularly its oxidation product, enterolactone (ENL), on prevention of hormone-dependent diseases, such as osteoporosis, cardiovascular diseases, hyp...
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Article
Recent advances and safety issues of transgenic plant-derived vaccines
Transgenic plant-derived vaccines comprise a new type of bioreactor that combines plant genetic engineering technology with an organism's immunological response. This combination can be considered as a bioreac...
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Article
Erratum to: Chryseobacterium zhengzhouense sp. nov., isolated from groundwater of a well in a vegetable field
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Article
Open AccessThe impact of DO and salinity on microbial community in poly(butylene succinate) denitrification reactors for recirculating aquaculture system wastewater treatment
The interactions between environmental factors and bacterial community shift in solid-phase denitrification are crucial for optimum operation of a reactor and to achieve maximum treatment efficiency. In this s...
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Open AccessRapid optimization of spore production from Bacillus amyloliquefaciens in submerged cultures based on dipicolinic acid fluorimetry assay
Some optimization techniques have been widely applied for spore fermentation based on the plate counting. This study optimized the culture medium for the spore production of Bacillus amyloliquefaciens BS-20 and i...
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Open AccessMesenchymal stem cells desensitize castration-resistant prostate cancer to docetaxel chemotherapy via inducing TGF-β1-mediated cell autophagy
Mesenchymal stem cells (MSCs) have been proved to drive castration resistant prostate cancer (CRPC). In this study, we aim to investigate the contribution of MSCs to the development of docetaxel resistance in ...
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Article
Open AccessInvestigation of hub gene associated with the infection of Staphylococcus aureus via weighted gene co-expression network analysis
Staphylococcus aureus is a gram-positive bacterium that causes serious infection. With the increasing resistance of bacteria to current antibiotics, it is necessary to learn more about the molecular mechanism an...
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Article
Open AccessThe numbers of fungi: contributions from traditional taxonomic studies and challenges of metabarcoding
The global diversity of fungi has been estimated using several different approaches. There is somewhere between 2–11 million estimated species, but the number of formally described taxa is around 150,000, a ti...
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Article
Open AccessSpecific gastrointestinal microbiota profiles in Chinese Tan sheep are associated with lauric acid content in muscle
The biological mechanisms underlying meat quality remain unclear. Currently, many studies report that the gastrointestinal microbiota is essential for animal growth and performance. However, it is uncertain wh...
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Article
Open AccessIdentification of a novel thermostable transaminase and its application in L-phosphinothricin biosynthesis
Transaminase (TA) is a crucial biocatalyst for enantioselective production of the herbicide L-phosphinothricin (L-PPT). The use of enzymatic cascades has been shown to effectively overcome the unfavorable ther...
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Article
Open AccessEnhancing the expression of the unspecific peroxygenase in Komagataella phaffii through a combination strategy
The unspecific peroxygenase (UPO) from Cyclocybe aegerita (AaeUPO) can selectively oxidize C–H bonds using hydrogen peroxide as an oxygen donor without cofactors, which has drawn significant industrial attention....