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Metabolic engineering of Corynebacterium glutamicum for the efficient production of β-Alanine from glucose

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  1. Article

    Open Access

    Enhancing the expression of the unspecific peroxygenase in Komagataella phaffii through a combination strategy

    The unspecific peroxygenase (UPO) from Cyclocybe aegerita (AaeUPO) can selectively oxidize C–H bonds using hydrogen peroxide as an oxygen donor without cofactors, which has drawn significant industrial attention....

    Li-**ang Zhao, Shu-** Zou, Qi Shen, Ya-** Xue in Applied Microbiology and Biotechnology (2024)

  2. Article

    Open Access

    Identification of a novel thermostable transaminase and its application in L-phosphinothricin biosynthesis

    Transaminase (TA) is a crucial biocatalyst for enantioselective production of the herbicide L-phosphinothricin (L-PPT). The use of enzymatic cascades has been shown to effectively overcome the unfavorable ther...

    Han-Lin Liu, Pu-Hong Yi, Jia-Min Wu, Feng Cheng in Applied Microbiology and Biotechnology (2024)

  3. Article

    Open Access

    Specific gastrointestinal microbiota profiles in Chinese Tan sheep are associated with lauric acid content in muscle

    The biological mechanisms underlying meat quality remain unclear. Currently, many studies report that the gastrointestinal microbiota is essential for animal growth and performance. However, it is uncertain wh...

    Zhen LI, Ran Cui, Yu-Bei Wang, Ya-Biao Luo, Peng-**ang Xue, Qi-Guo Tang in BMC Microbiology (2023)

  4. Article

    Open Access

    The numbers of fungi: contributions from traditional taxonomic studies and challenges of metabarcoding

    The global diversity of fungi has been estimated using several different approaches. There is somewhere between 2–11 million estimated species, but the number of formally described taxa is around 150,000, a ti...

    Chayanard Phukhamsakda, Rolf Henrik Nilsson, Chitrabhanu S. Bhunjun in Fungal Diversity (2022)

  5. Article

    Open Access

    Investigation of hub gene associated with the infection of Staphylococcus aureus via weighted gene co-expression network analysis

    Staphylococcus aureus is a gram-positive bacterium that causes serious infection. With the increasing resistance of bacteria to current antibiotics, it is necessary to learn more about the molecular mechanism an...

    Jia-xin Li, Xun-jie Cao, Yuan-yi Huang, Ya-** Li, Zi-yuan Yu, Min Lin in BMC Microbiology (2021)

  6. Article

    Open Access

    Mesenchymal stem cells desensitize castration-resistant prostate cancer to docetaxel chemotherapy via inducing TGF-β1-mediated cell autophagy

    Mesenchymal stem cells (MSCs) have been proved to drive castration resistant prostate cancer (CRPC). In this study, we aim to investigate the contribution of MSCs to the development of docetaxel resistance in ...

    Yang Yu, Fu-han Yang, Wen-tao Zhang, Ya-dong Guo, Lin Ye, Xu-dong Yao in Cell & Bioscience (2021)

  7. Article

    Open Access

    Rapid optimization of spore production from Bacillus amyloliquefaciens in submerged cultures based on dipicolinic acid fluorimetry assay

    Some optimization techniques have been widely applied for spore fermentation based on the plate counting. This study optimized the culture medium for the spore production of Bacillus amyloliquefaciens BS-20 and i...

    Hang Ren, Ya-ting Su, **ao-hua Guo in AMB Express (2018)

  8. Article

    Open Access

    The impact of DO and salinity on microbial community in poly(butylene succinate) denitrification reactors for recirculating aquaculture system wastewater treatment

    The interactions between environmental factors and bacterial community shift in solid-phase denitrification are crucial for optimum operation of a reactor and to achieve maximum treatment efficiency. In this s...

    Ya-Le Deng, Yun-Jie Ruan, Song-Ming Zhu, **-Shan Guo, Zhi-Ying Han in AMB Express (2017)

  9. Article

    Erratum to: Chryseobacterium zhengzhouense sp. nov., isolated from groundwater of a well in a vegetable field

    Ya-Nan Wang, Wei-Hong He, Ming-Li An, Wen-Yu Tian, **ao-Yan You in Antonie van Leeuwenhoek (2017)

  10. Article

    Recent advances and safety issues of transgenic plant-derived vaccines

    Transgenic plant-derived vaccines comprise a new type of bioreactor that combines plant genetic engineering technology with an organism's immunological response. This combination can be considered as a bioreac...

    Zheng-jun Guan, Bin Guo, Yan-lin Huo in Applied Microbiology and Biotechnology (2013)

  11. Article

    Open Access

    Production of enterodiol from defatted flaxseeds through biotransformation by human intestinal bacteria

    The effects of enterolignans, e.g., enterodiol (END) and particularly its oxidation product, enterolactone (ENL), on prevention of hormone-dependent diseases, such as osteoporosis, cardiovascular diseases, hyp...

    Cheng-Zhi Wang, **ao-Qing Ma, Dong-Hui Yang, Zhi-Rong Guo, Gui-Rong Liu in BMC Microbiology (2010)