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BK channels affect glucose homeostasis and cell viability of murine pancreatic beta cells
Evidence is accumulating that Ca2+-regulated K+ (KCa) channels are important for beta cell function. We used BK channel knockout (BK-KO) mice to examine the role of these KCa channels for glucose homeostasis, bet...
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40th EASD Annual Meeting of the European Association for the Study of Diabetes
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Direct interference of HIV protease inhibitors with pancreatic β-cell function
The aim of the present study was to evaluate whether HIV protease inhibitors directly interfere with stimulus-secretion coupling in pancreatic β-cells. Insulin secretion was determined by a radioimmunoassay (R...