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  1. Article

    Open Access

    Frequent allelic deletion at the FHIT locus associated with p53 overexpression in squamous cell carcinoma subtype of Taiwanese non-small-cell lung cancers

    The fragile histidine triad (FHIT) gene, encompassing the FRA3B fragile site at chromosome 3p14.2, is a tumour suppressor gene involved in different tumour types including non-small-cell lung cancers (NSCLCs)....

    Y-C Lee, C-T Wu, J-Y Shih, Y-S Jou, Y-L Chang in British Journal of Cancer (2004)

  2. No Access

    Article

    More evidence supports the association of PPP3CC with schizophrenia

    Calcineurin is a calcium/calmodulin-dependent protein phosphatase composed of two subunits, a regulatory subunit of calcineurin B (CNB) and a catalytic subunit of calcineurin A (CNA). PPP3CC is the γ isoform of C...

    Y L Liu, C S J Fann, C M Liu, C C Chang, W C Yang, S I Hung, S L Yu in Molecular Psychiatry (2007)

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    Article

    Somatic LMCD1 mutations promoted cell migration and tumor metastasis in hepatocellular carcinoma

    Common genetic alteration in cancer genomes is implicated for embracing an aberrant cancer gene participated in tumor progression. In this study, we identified a somatic mutated LIM and cysteine-rich domains-1...

    C-Y Chang, S-C Lin, W-H Su, C-M Ho, Y-S Jou in Oncogene (2012)