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  1. Article

    TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model

    Death receptor-mediated hepatocyte apoptosis is implicated in a wide range of liver diseases including viral and alcoholic hepatitis, ischemia/reperfusion injury, fulminant hepatic failure, cholestatic liver i...

    F J Cubero, A Singh, E Borkham-Kamphorst, Y A Nevzorova in Cell Death & Differentiation (2013)

  2. Article

    Open Access

    Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model

    Chronic liver inflammation is a crucial event in the development and growth of hepatocellular carcinoma (HCC). Compelling evidence has shown that interleukin-6 (IL-6)/gp130-dependent signaling has a fundamenta...

    M Hatting, M Spannbauer, J Peng, M Al Masaoudi, G Sellge in Cell Death & Disease (2015)