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Article
Open AccessLack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model
Chronic liver inflammation is a crucial event in the development and growth of hepatocellular carcinoma (HCC). Compelling evidence has shown that interleukin-6 (IL-6)/gp130-dependent signaling has a fundamenta...
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Article
TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model
Death receptor-mediated hepatocyte apoptosis is implicated in a wide range of liver diseases including viral and alcoholic hepatitis, ischemia/reperfusion injury, fulminant hepatic failure, cholestatic liver i...