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Article

Mitochondrial dysfunction induces radioresistance in colorectal cancer by activating [Ca²⁺]_m-PDP1-PDH-histone acetylation retrograde signaling

Mitochondrial retrograde signaling (mito-RTG) triggered by mitochondrial dysfunction plays a potential role in regulating tumor metabolic reprogramming and cellular sensitivity to radiation. Our previous studi...

Yingying Shi, You Wang, Huangang Jiang, Xuehua Sun, Hui Xu, Xue Wei… in Cell Death & Disease (2021)