![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
217 Result(s)
-
Article
Effectiveness and safety of pharmacological prophylaxis for chronic migraine: a systematic review and network meta-analysis
Chronic migraine (CM) significantly impacts both the physical and mental health of patients. Current studies on the safety and effectiveness of different pharmacological prophylaxis interventions for CM are li...
-
Article
Open AccessRisk factors and management of gastrointestinal bleeding in patients with or without antiplatelet and anticoagulation therapy: a multicenter real-world prospective study
Antiplatelet and anticoagulation drugs complicate acute gastrointestinal bleeding (GIB) patients. Limited data about the risk factors and patient management has been presented. This study explored the associat...
-
Article
Open AccessTrends in parkinson’s disease mortality in China from 2004 to 2021: a joinpoint analysis
This study aimed to analyze the trends of Parkinson’s disease (PD) mortality rates among Chinese residents from 2004 to 2021, provide evidence for the formulation of PD prevention and control strategies to imp...
-
Article
Open AccessA porcine kidney-derived clonal cell line with clear genetic annotation is highly susceptible to African swine fever virus
African Swine Fever virus (ASFV), the causative agent of African swine fever, is a highly lethal hemorrhagic virus affecting domestic pigs and wild boars. The primary target cells for ASFV infection are porcin...
-
Article
Associations of slee** patterns and isotemporal substitution of other behavior with the prevalence of CKD in Chinese adults
Studies have found a U-shaped relationship between sleep duration and chronic kidney disease (CKD) risk, but limited research evaluated the association of reallocating excessive sleep to other behavior with CK...
-
Article
Open AccessThe efficacy of bandage contact lens in relieving the aggravation of dry eye disease after complicated cataract or/and IOL surgery
In the present study, we aimed to evaluate the efficacy of the bandage contact lens (BCLs) in the treatment of dry eye disease (DED) after complicated cataract or/and intraocular lens (IOL) surgery.
-
Article
Open AccessCortical lipid metabolic pathway alteration of early Alzheimer’s disease and candidate drugs screen
Lipid metabolism changes occur in early Alzheimer's disease (AD) patients. Yet little is known about metabolic gene changes in early AD cortex.
-
Article
Open AccessDevelopment of a lateral flow immunochromatography assay for the detection of fluoroacetamide in blood samples
Fluoroacetamide (FAM) has been employed as a rodenticide for an extended duration, leading to a multitude of incidents involving human ingestion poisoning. Currently, FAMs have been prohibited by nations globa...
-
Article
Open AccessCVOT Summit Report 2023: new cardiovascular, kidney, and metabolic outcomes
The 9th Cardiovascular Outcome Trial (CVOT) Summit: Congress on Cardiovascular, Kidney, and Metabolic Outcomes was held virtually on November 30-December 1, 2023. This reference congress served as a platform f...
-
Article
Open AccessClinical features and genetic spectrum of a multicenter Chinese cohort with myotonic dystrophy type 1
As the most common subtype of adult muscular dystrophy worldwide, large cohort reports on myotonic dystrophy type I (DM1) in China are still lacking. This study aims to analyze the genetic and clinical charact...
-
Article
Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function variants in TMEM141, DDHD2, and LHFPL5
Highly clinical and genetic heterogeneity of neurodevelopmental disorders presents a major challenge in clinical genetics and medicine. Panoramic variation analysis is imperative to analyze the disease phenoty...
-
Article
Association between primary Sjögren’s syndrome and gut microbiota disruption: a systematic review and meta-analysis
Evidence of gut microbiota disruption for numerous autoimmune diseases has accumulated. Recently, the relationship between the microbiota and primary Sjögren’s disease has been increasingly investigated but ha...
-
Article
Open AccessRelationship between paravertebral muscle function, pelvic incidence, and health-related quality of life in patients with degenerative spinal deformity
Patients with degenerative spinal deformity often experience symptoms that seriously affect their quality of life, such as low back pain and dysfunction. This study aimed to investigate the relationship betwee...
-
Article
Open AccessPredictive value of adipokines for the severity of acute pancreatitis: a meta-analysis
Severe acute pancreatitis (SAP) is a dangerous condition with a high mortality rate. Many studies have found an association between adipokines and the development of SAP, but the results are controversial. The...
-
Article
Quantitative multi-parameter assessment of age- and gender-related variation of back extensor muscles in healthy adults using Dixon MR imaging
Investigate sex differences in age-related back extensor muscle degeneration using Dixon MRI and analyze the relationship between quantitative muscle parameters and back muscle strength in healthy adults.
-
Article
Open AccessEfficacy and safety of voriconazole in the treatment of invasive pulmonary aspergillosis in patients with liver failure: study protocol for a randomized controlled clinical trial
Acute-on-chronic liver failure (ACLF) is a common clinical type of liver failure, and patients with acute-on-chronic liver failure are prone to fungal infections, especially the increasing incidence of invasiv...
-
Article
Open AccessMap** brain functional networks topological characteristics in new daily persistent headache: a magnetoencephalography study
The brain functional network topology in new daily persistent headache (NDPH) is not well understood. In this study, we aim to assess the cortical functional network topological characteristics of NDPH using n...
-
Article
Open AccessApplication of Hydrogels in Cardiac Regeneration
Myocardial infarction (MI) is a leading cause of death globally. Due to limited cardiac regeneration, infarcted myocardial tissue is gradually replaced by cardiac fibrosis, causing cardiac dysfunction, arrhyth...
-
Article
Change in Mineral Status After Bariatric Surgery: a Meta-analysis
The risk of protein and vitamin deficiencies after bariatric surgery has been well studied, but the change in mineral status has not gotten enough attention. This study aimed to perform a meta-analysis regardi...
-
Article
Open AccessIncreased glymphatic system activity in migraine chronification by diffusion tensor image analysis along the perivascular space
Preliminary evidence suggests that several headache disorders may be associated with glymphatic dysfunction. However, no studies have been conducted to examine the glymphatic activity in migraine chronification.