25 Result(s)

Article

SOFA in sepsis: with or without GCS

Sepsis is a global public health burden. The sequential organ failure assessment (SOFA) is the most commonly used scoring system for diagnosing sepsis and assessing severity. Due to the widespread use of endot...

Lu Wang, Xudong Ma, Guanghua Zhou, Sifa Gao… in European Journal of Medical Research (2024)

Article

Identification and validation of IRF6 related to ovarian cancer and biological function and prognostic value

Ovarian cancer (OC) is a severe gynecological malignancy with significant diagnostic and therapeutic challenges. The discovery of reliable cancer biomarkers can be used to adjust diagnosis and improve patient ...

Shihao Hong, Ni Fu, Shanliang Sang, Xudong Ma, Fangying Sun… in Journal of Ovarian Research (2024)

Article

Multicompartmental coacervate-based protocell by spontaneous droplet evaporation

Hierarchical compartmentalization, a hallmark of both primitive and modern cells, enables the concentration and isolation of biomolecules, and facilitates spatial organization of biochemical reactions. Coacerv...

Cheng Qi, Xudong Ma, Qi Zeng, Zhangwei Huang, Shanshan Zhang… in Nature Communications (2024)

Article

Factors influencing DVT formation in sepsis

Sepsis is a global public health burden. Deep vein thrombosis (DVT) is the third most common cause of death from cardiovascular disease after heart attacks and strokes. We designed this experiment to investiga...

Lu Wang, Xudong Ma, Yujie Chen, Sifa Gao, Wei Pan, Jieqing Chen… in Thrombosis Journal (2024)

Article

Carbapenem is not always the best choice in the treatment of septic shock

Septic shock is a global public health burden. In addition to the improvement of the level of individual care, the improvement of the overall hospital quality control management is also an essential key aspect...

Lu Wang, Xudong Ma, Yujie Chen, Sifa Gao, Huaiwu He… in European Journal of Medical Research (2023)

Article

Measuring the worldwide spread of COVID-19 using a comprehensive modeling method

With the global spread of COVID-19, detecting high-risk countries/regions timely and dynamically is essential; therefore, we sought to develop automatic, quantitative and scalable analysis methods to observe a...

**ang Zhou, Xudong Ma, Sifa Gao, Yingying Ma… in BMC Medical Informatics and Decision Making (2023)

Article

Evaluation of ICUs and weight of quality control indicators: an exploratory study based on Chinese ICU quality data from 2015 to 2020

This study aimed to explore key quality control factors that affected the prognosis of intensive care unit (ICU) patients in Chinese mainland over six years (2015–2020). The data for this study were from 31 pr...

Longxiang Su, Xudong Ma, Sifa Gao, Zhi Yin, Yujie Chen, Wenhu Wang… in Frontiers of Medicine (2023)

Article

Correction: Regulation of PPARγ/CPT-1 expression ameliorates cochlear hair cell injury by regulating cellular lipid metabolism and oxidative stress

**aorong Niu, Peng Han, Junsong Liu, Zichen Chen… in Molecular Genetics and Genomics (2023)

Article

Only the new beginning of VAP quality control

**n Ding, Xudong Ma, **ang Zhou in Critical Care (2023)

Article

Association between quality control and outcomes of septic shock caused by intestinal perforation in China: a cross-sectional study

Septic shock, largely caused by intestinal perforation, is a common critical disease in intensive care unit (ICU). For hospitals and health systems, a performance improvement program for sepsis was strong reco...

Lu Wang, Xudong Ma, Huaiwu He, Longxiang Su, Yanhong Guo… in Scientific Reports (2023)

Article

Effect of ICU quality control indicators on VAP incidence rate and mortality: a retrospective study of 1267 hospitals in China

To investigate the effects of ICU quality control indicators on the VAP incidence rate and mortality in China throughout 2019.

**n Ding, Xudong Ma, Sifa Gao, Longxiang Su, Guangliang Shan, Yaoda Hu… in Critical Care (2022)

Article

Correction to: Association between hospital and ICU structural factors and patient outcomes in China: a secondary analysis of the National Clinical Improvement System Data in 2019

Zhen Li, Xudong Ma, Sifa Gao, Qi Li, Hongbo Luo, Jianhua Sun, Wei Du… in Critical Care (2022)

Article

Association between hospital and ICU structural factors and patient outcomes in China: a secondary analysis of the National Clinical Improvement System Data in 2019

Hospital and ICU structural factors are key factors affecting the quality of care as well as ICU patient outcomes. However, the data from China are scarce. This study was designed to investigate how difference...

Zhen Li, Xudong Ma, Sifa Gao, Qi Li, Hongbo Luo, Jianhua Sun, Wei Du… in Critical Care (2022)

Article

Analysis of structure indicators influencing 3-h and 6-h compliance with the surviving sepsis campaign guidelines in China: a systematic review

Compliance with the surviving sepsis campaign (SSC) guidelines (C_ssc) is a key factor affecting the effects of sepsis treatment. We designed this study to investigate the relationships of the structure indicators...

Lu Wang, Xudong Ma, Huaiwu He, Longxiang Su… in European Journal of Medical Research (2021)

Article

Loss of PLK2 induces acquired resistance to temozolomide in GBM via activation of notch signaling

Glioblastoma (GBM) is a lethal type of primary brain tumor with a median survival less than 15 months. Despite the recent improvements of comprehensive strategies, the outcomes for GBM patients remain dismal. ...

Wahafu Alafate, Dongze Xu, Wei Wu… in Journal of Experimental & Clinical Cancer … (2020)

Article

miR-100 inhibits cell proliferation in mantle cell lymphoma by targeting mTOR

miR-100 is reported to be associated with cell proliferation and apoptosis. However, the function of miR-100 in mantle cell lymphoma (MCL) is unknown. The purpose of this study is to analyze the abnormal expre...

Luhui Lin, Yiqun Huang, Wei Zhuang, ** Lin… in Experimental Hematology & Oncology (2020)

Article

Effects of a national quality improvement program on ICUs in China: a controlled pre-post cohort study in 586 hospitals

Patient safety and critical care quality remain a challenging issue in the ICU. However, the effects of the national quality improvement (QI) program remain unknown in China.

Huaiwu He, Xudong Ma, Longxiang Su, Lu Wang, Yanhong Guo, Guangliang Shan… in Critical Care (2020)

Article

Genome-wide characterization of NtHD-ZIP IV: different roles in abiotic stress response and glandular Trichome induction

The plant-specific homeodomain-leucine zipper class IV (HD-ZIP IV) gene family has been involved in the regulation of epidermal development.

Hongying Zhang, Xudong Ma, Wenjiao Li, Dexin Niu, Zhaojun Wang… in BMC Plant Biology (2019)

Article

Genetic variants in CYP4F2 were significantly correlated with susceptibility to ischemic stroke

Ischemic stroke (IS) is a serious cardiovascular disease and is associated with several single nucleotide polymorphisms (SNPs). However, the role of Cytochrome P450 family 4 subfamily F member 2 (CYP4F2) gene in ...

Yuan Wu, Junjie Zhao, Yonglin Zhao, Tingqin Huang, Xudong Ma… in BMC Medical Genetics (2019)

Article

MDM4 contributes to the increased risk of glioma susceptibility in Han Chinese population

Recently, MDM4 gene has been reported to be a susceptibility gene for glioma in Europeans, but the molecular mechanism of glioma pathogenesis remains unknown. The aim of this study was to investigate whether comm...

Peng Sun, Feng Yan, Wei Fang, Junjie Zhao, Hu Chen, Xudong Ma… in Scientific Reports (2018)