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  1. Article

    Open Access

    Missing genes in the annotation of prokaryotic genomes

    Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports that prokaryotic gene finder programs hav...

    Andrew S Warren, Jeremy Archuleta, Wu-chun Feng, João Carlos Setubal in BMC Bioinformatics (2010)

  2. Article

    Open Access

    Multi-dimensional characterization of electrostatic surface potential computation on graphics processors

    Calculating the electrostatic surface potential (ESP) of a biomolecule is critical towards understanding biomolecular function. Because of its quadratic computational complexity (as a function of the number of at...

    Mayank Daga, Wu-chun Feng in BMC Bioinformatics (2012)

  3. Article

    Open Access

    muBLASTP: database-indexed protein sequence search on multicore CPUs

    The Basic Local Alignment Search Tool (BLAST) is a fundamental program in the life sciences that searches databases for sequences that are most similar to a query sequence. Currently, the BLAST algorithm utili...

    **g Zhang, Sanchit Misra, Hao Wang, Wu-chun Feng in BMC Bioinformatics (2016)