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  1. Article

    Open Access

    muBLASTP: database-indexed protein sequence search on multicore CPUs

    The Basic Local Alignment Search Tool (BLAST) is a fundamental program in the life sciences that searches databases for sequences that are most similar to a query sequence. Currently, the BLAST algorithm utili...

    **g Zhang, Sanchit Misra, Hao Wang, Wu-chun Feng in BMC Bioinformatics (2016)

  2. Article

    Open Access

    High-performance biocomputing for simulating the spread of contagion over large contact networks

    Many important biological problems can be modeled as contagion diffusion processes over interaction networks. This article shows how the EpiSimdemics interaction-based simulation system can be applied to the g...

    Keith R Bisset, Ashwin M Aji, Madhav V Marathe, Wu-chun Feng in BMC Genomics (2012)

  3. Article

    Open Access

    Multi-dimensional characterization of electrostatic surface potential computation on graphics processors

    Calculating the electrostatic surface potential (ESP) of a biomolecule is critical towards understanding biomolecular function. Because of its quadratic computational complexity (as a function of the number of at...

    Mayank Daga, Wu-chun Feng in BMC Bioinformatics (2012)

  4. Article

    Open Access

    Missing genes in the annotation of prokaryotic genomes

    Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports that prokaryotic gene finder programs hav...

    Andrew S Warren, Jeremy Archuleta, Wu-chun Feng, João Carlos Setubal in BMC Bioinformatics (2010)