7 Result(s)
within
Wouter Graumans
English
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessEstimating female malaria mosquito age by quantifying Y-linked genes in stored male spermatozoa
Vector control strategies are among the most effective measures to combat mosquito-borne diseases, such as malaria. These strategies work by altering the mosquito age structure through increased mortality of t...
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Article
Open AccessOutcomes of controlled human malaria infection after BCG vaccination
Recent evidence suggests that certain vaccines, including Bacillus-Calmette Guérin (BCG), can induce changes in the innate immune system with non-specific memory characteristics, termed ‘trained immunity’. Her...
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Article
Open AccessPublisher Correction: Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity
The original version of this Article contained errors in Fig. 3. In panel a, bars from a chart depicting the percentage of antibody-positive individuals in non-infectious and infectious groups were inadvertent...
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Article
Open AccessUnravelling the immune signature of Plasmodium falciparum transmission-reducing immunity
Infection with Plasmodium can elicit antibodies that inhibit parasite survival in the mosquito, when they are ingested in an infectious blood meal. Here, we determine the transmission-reducing activity (TRA) of n...
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Article
Open AccessProbabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites
Plasmodium gametocytes are the sexual forms of the malaria parasite essential for transmission to mosquitoes. To better understand how gametocytes differ from asexual blood-stage parasites, we pe...
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Article
Open AccessVariation in susceptibility of African Plasmodium falciparum malaria parasites to TEP1 mediated killing in Anopheles gambiae mosquitoes
Anopheles gambiae s.s. mosquitoes are efficient vectors for Plasmodium falciparum, although variation exists in their susceptibility to infection. This variation depends partly on the thioester-containing protein...
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Article
Open AccessThe relevance and applicability of oocyst prevalence as a read-out for mosquito feeding assays
Mosquito feeding assays are important in evaluations of malaria transmission-reducing interventions. The proportion of mosquitoes with midgut oocysts is commonly used as an outcome measure, but in natural low ...
