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  1. Article

    Open Access

    CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells

    Glioblastoma (GB) remains the most aggressive primary brain malignancy. Adoptive transfer of chimeric antigen receptor (CAR)-modified immune cells has emerged as a promising anti-cancer approach, yet the poten...

    Jianfeng Han, Jianhong Chu, Wing Keung Chan, Jianying Zhang in Scientific Reports (2015)

  2. Article

    Open Access

    Genome-wide single-nucleotide polymorphism analysis revealed SUFU suppression of acute graft-versus-host disease through downregulation of HLA-DR expression in recipient dendritic cells

    Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). To identify recipient risk factors, a genome-wide study was perform...

    Rafijul Bari, Christine Hartford, Wing Keung Chan, Queenie Vong in Scientific Reports (2015)