5 Result(s)

Article

A deep catalogue of protein-coding variation in 983,578 individuals

Rare coding variants that substantially affect function provide insights into the biology of a gene^1–3. However, ascertaining the frequency of such variants requires large sample sizes^4–8. Here we present a catal...

Kathie Y. Sun, **aodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor… in Nature (2024)

Article

Author Correction: Genoty**, sequencing and analysis of 140,000 adults from Mexico City

Andrey Ziyatdinov, Jason Torres, Jesús Alegre-Díaz, Joshua Backman… in Nature (2024)

Article

Genoty**, sequencing and analysis of 140,000 adults from Mexico City

The Mexico City Prospective Study is a prospective cohort of more than 150,000 adults recruited two decades ago from the urban districts of Coyoacán and Iztapalapa in Mexico City¹. Here we generated genotype and ...

Andrey Ziyatdinov, Jason Torres, Jesús Alegre-Díaz, Joshua Backman… in Nature (2023)

Article

Launching genomics into the cloud: deployment of Mercury, a next generation sequence analysis pipeline

Massively parallel DNA sequencing generates staggering amounts of data. Decreasing cost, increasing throughput, and improved annotation have expanded the diversity of genomics applications in research and clin...

Jeffrey G Reid, Andrew Carroll, Narayanan Veeraraghavan… in BMC Bioinformatics (2014)

Article

Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum

The social amoebae (Dictyostelia) are a diverse group of Amoebozoa that achieve multicellularity by aggregation and undergo morphogenesis into fruiting bodies with terminally differentiated spores and stalk ce...

Richard Sucgang, Alan Kuo, **angjun Tian, William Salerno, Anup Parikh… in Genome Biology (2011)