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Mutation in Single-Cell Systems Induced by Low-Level Mutagen Exposure

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  1. Article

    Open Access

    Map** mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis

    The growth of tumor cells is accompanied by mutations in nuclear and mitochondrial genomes creating marked genetic heterogeneity. Tumors also contain non-tumor cells of various origins. An observed somatic mit...

    Paulo Refinetti, Christian Arstad, William G. Thilly in BMC Clinical Pathology (2017)

  2. Article

    Open Access

    The study of calcified atherosclerotic arteries: an alternative to evaluate the composition of a problematic tissue reveals new insight including metakaryotic cells

    Calcifications of atherosclerotic plaques represent a controversial issue as they either lead to the stabilization or rupture of the lesion. However, the cellular key players involved in the progression of the...

    Silvia Fittipaldi, Francesco Vasuri, Alessio Degiovanni in BMC Clinical Pathology (2016)