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  1. No Access

    Article

    Multistage carcinogenesis and the fraction at risk

    Multistage carcinogenesis models describe the evolution of the cells in an individual’s organ from a normal stage to a pre-neoplastic stage to a neoplastic stage. The triggers for the passage from one stage to...

    Stephan Morgenthaler, Pablo Herrero, William G. Thilly in Journal of Mathematical Biology (2004)

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    Chapter and Conference Paper

    A Stochastic Model of Carcinogenesis

    This paper derives the age-dependent risk of a theoretical model of carcinogenesis incorporating the familiar notions of multiple stages (initiation, promotion and progression). It is assumed that initiation i...

    Pablo Herrero, William G. Thilly… in Statistics in Genetics and in the Environm… (2001)