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  1. No Access

    Protocol

    Engineering HSV-1 Vectors for Gene Therapy

    Virus vectors have been employed as gene transfer vehicles for various preclinical and clinical gene therapy applications and with the approval of Glybera (Alipogene tiparvovec) as the first gene therapy produ...

    William F. Goins, Shaohua Huang, Bonnie Hall, Marco Marzulli in Herpes Simplex Virus (2020)

  2. Article

    Open Access

    Current gene therapy using viral vectors for chronic pain

    The complexity of chronic pain and the challenges of pharmacotherapy highlight the importance of development of new approaches to pain management. Gene therapy approaches may be complementary to pharmacotherap...

    Jean-Marc G Guedon, Shaogen Wu, Xuexing Zheng, Caroline C Churchill in Molecular Pain (2015)

  3. No Access

    Protocol

    Engineering HSV-1 Vectors for Gene Therapy

    Virus vectors have been employed as gene transfer vehicles for various preclinical and clinical gene therapy applications, and with the approval of Glybera (alipogene tiparvovec) as the first gene therapy prod...

    William F. Goins, Shaohua Huang, Justus B. Cohen in Herpes Simplex Virus (2014)

  4. Article

    Correction: Progress in gene therapy for neurological disorders

    Nat. Rev. Neurol. 9, 277–291 (2013); doi:10.1038/nrneurol.2013.56 In the version of this article initially published, HSV-1‒thymidine kinase was incorrectly referred to as tyrosine kinase in Table 4, and as HS...

    Michele Simonato, Jean Bennett, Nicholas M. Boulis in Nature Reviews Neurology (2013)

  5. No Access

    Article

    Progress in gene therapy for neurological disorders

    Neurological diseases that result from an underlying genetic mutation or from acquired genetic and/or epigenetic changes are prevalent in the population, and might be amenable to gene therapy. In this Review, ...

    Michele Simonato, Jean Bennett, Nicholas M. Boulis in Nature Reviews Neurology (2013)