10 Result(s)
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Article
Open AccessSmartphone-assisted training with education for patients with hip and/or knee osteoarthritis (SmArt-E): study protocol for a multicentre pragmatic randomized controlled trial
Hip and knee osteoarthritis are associated with functional limitations, pain and restrictions in quality of life and the ability to work. Furthermore, with growing prevalence, osteoarthritis is increasingly ca...
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Open AccessBlinded sample size re-estimation in a comparative diagnostic accuracy study
The sample size calculation in a confirmatory diagnostic accuracy study is performed for co-primary endpoints because sensitivity and specificity are considered simultaneously. The initial sample size calculat...
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Article
Open AccessSociodemographic aspects and health care-related outcomes: a latent class analysis of informal dementia care dyads
Studies revealed the importance to assess dementia care dyads, composed of persons with dementia and their primary informal caregivers, in a differentiated way and to tailor support services to particular livi...
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Effectiveness and cost-effectiveness of an integrated care program for schizophrenia: an analysis of routine data
In Germany, a regional social health insurance fund provides an integrated care program for patients with schizophrenia (IVS). Based on routine data of the social health insurance, this evaluation examined the...
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Article
New diagnostic markers in salivary gland tumors
Parotid gland tumors are a rare and heterogeneous entity. Molecular markers are sparse. The aim of the study was to identify new diagnostic markers in benign and malignant salivary tumors. A tissue microarray ...
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A prospective, randomised, multicenter trial for surgical treatment of central retinal vein occlusion: results of the Radial Optic Neurotomy for Central Vein Occlusion (ROVO) study group
To compare the surgical outcomes and evaluate the effectiveness of two treatments for central retinal vein occlusion (CRVO), radial optic neurotomy (RON) and intravitreal triamcinolone (IVT), in comparison to ...
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Article
Enhanced Serotonin Transporter Function during Depression in Seasonal Affective Disorder
Decreased synaptic serotonin during depressive episodes is a central element of the monoamine hypothesis of depression. The serotonin transporter (5-HTT, SERT) is a key molecule for the control of synaptic ser...
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Role of amiodarone on the systemic inflammatory response induced by cardiac surgery: proinflammatory actions
Amiodarone (AMIO), a widely used anti-arrhythmic drug, has been shown to reduce the incidence of atrial fibrillation after cardiac surgery and also to exert immunomodulatory actionsin vitro and proinflammatory ef...
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Article
Plasma levels of polyunsaturated fatty acids in children with atopic dermatitis and in atopic and nonatopic controls
BACKGROUND: Atopic dermatitis has been thought to be associated with a disturbance in n-6 polyunsaturated fatty acid (PUFA) metabolism, but randomized trials investigating the clinical efficacy of oral supplem...
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Article
Impaired Gastric Emptying and Altered Intragastric Meal Distribution in Diabetes Mellitus Related to Autonomic Neuropathy?
Previous studies in diabetic patients suggested a relationship between delayed gastric emptying and increased ingesta retention in either proximal or distal stomach, but the determinants underlying these abnor...
