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Article
Open AccessMAPK4 silencing in gastric cancer drives liver metastasis by positive feedback between cancer cells and macrophages
Liver metastasis is a major cause of death in gastric cancer patients, but the underlying mechanisms are poorly understood. Through a combination of in vivo screening and transcriptome profiling followed by qu...
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Article
The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study
In clinical practice, PTB patients have concurrent many types of comorbidities such as pneumonia, liver disorder, diabetes mellitus, hematological disorder, and malnutrition. Detecting and treating specific co...
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Article
Targeting Cholinesterase Inhibitor Poisoning with a Novel Blocker Against Both Nicotinic and Muscarinic Receptors
Clinicians have been treating poisoning by acetylcholinesterase inhibitors (ChEI) for more than half a century. However, the current atropine-centered therapy still cannot protect completely against all ChEIs,...