-
Article
Morphine Induced Neuroprotection in Ischemic Stroke by Activating Autophagy Via mTOR-Independent Activation of the JNK1/2 Pathway
Morphine (Mor) has exhibited efficacy in safeguarding neurons against ischemic injuries by simulating ischemic/hypoxic preconditioning (I/HPC). Concurrently, autophagy plays a pivotal role in neuronal survival...
-
Article
Open AccessRetraction Note: Optimization of oncolytic effect of Newcastle disease virus Clone30 by selecting sensitive tumor host and constructing more oncolytic viruses
-
Article
Open AccessA privacy-preserving image retrieval scheme with access control based on searchable encryption in media cloud
With the popularity of the media cloud computing industry, individuals and organizations outsource image computation and storage to the media cloud server to reduce the storage burden. Media images usually con...
-
Article
ONMCA: One-Network-Multi-Chain Architecture for customizable asset-oriented blockchain systems
The development of modern digital economies requires trusted digital asset management (DAM), for which blockchain technology is increasingly being adopted. However, the current architecture for constructing bl...
-
Article
The unique nature and psychosocial implications of awe
Psychological research has explored awe’s intricate nature and far-reaching consequences. Awe profoundly influences the sense of self (which has considerable psychosocial implications), but there are complexit...
-
Article
Open AccessLinear ubiquitination regulates the KSHV replication and transcription activator protein to control infection
Like many other viruses, KSHV has two life cycle modes: the latent phase and the lytic phase. The RTA protein from KSHV is essential for lytic reactivation, but how this protein’s activity is regulated is not ...
-
Article
Distributed generalized Nash equilibrium seeking: event-triggered coding-decoding-based secure communication
In this paper, we consider the distributed generalized Nash equilibrium (GNE) seeking problem in strongly monotone games. The transmission among players is implemented through a digital communication network w...
-
Article
Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis
Ochratoxin A (OTA), a secondary fungal metabolite known for its nephrotoxic effects, is prevalent in various feeds and food items. Our recent study suggests that OTA-induced nephrotoxicity is linked to the Sig...
-
Article
Modulating cross-linked network structure of epoxy resin blends towards concurrently high intrinsic thermal conductivity and dielectric properties
High thermal conductivity (k) epoxy resin (EP) composites are widely used in electronic devices and power equipment where timely heat dissipation is urgently desirable. However, achieving a balance between high-k...
-
Article
Analysis of chitinase gene family in barley and function study of HvChi22 involved in drought tolerance
Chitinase (Chi) is a pathogenesis-related protein, also reported to play an important role in plant responses to abiotic stress. However, its role in response to abiotic stress in barley is still unclear.
-
Article
Study of the Recovery and Purification of Copper from the Recycling of Motherboard Waste and Its Application for Nanoparticle Synthesis
Metals can be reused from different residues as an alternative for the synthesis of nanoparticles. This can add value to the recycling process through the reuse of raw materials, the mitigation of contaminatio...
-
Article
Cell-derived biomimetic nanoparticles for the targeted therapy of ALI/ARDS
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common clinical critical diseases with high morbidity and mortality. Especially since the COVID-19 outbreak, the mortality rates of cr...
-
Article
Open AccessLow-Shear Stress Promotes Atherosclerosis via Inducing Endothelial Cell Pyroptosis Mediated by IKKε/STAT1/NLRP3 Pathway
Atherosclerosis is initiated by vascular endothelial dysfunction, and low-shear stress (LSS) of blood flow is a key factor leading to endothelial dysfunction. Growing evidence suggests that endothelial cell py...
-
Article
Awe fosters positive attitudes toward solitude
Research in psychological science has predominantly focused on the importance of social interaction to health and well-being, neglecting how solitude relates to optimal functioning. Although solitude is someti...
-
Article
CAV1 Protein Encapsulated in Mouse BMSC-Derived Extracellular Vesicles Alleviates Myocardial Fibrosis Following Myocardial Infarction by Blocking the TGF-β1/SMAD2/c-JUN Axis
Extracellular vesicles (EVs) derived from mouse bone marrow mesenchymal stem cells (mBMSCs) convey the CAV1 protein, influencing the TGF-β1/SMAD2/c-JUN pathway and thus the molecular mechanisms underlying myoc...
-
Article
Open AccessMulti-Physics Coupled Acoustic-Mechanics Analysis and Synergetic Optimization for a Twin-Fluid Atomization Nozzle
Fine particulate matter produced during the rapid industrialization over the past decades can cause significant harm to human health. Twin-fluid atomization technology is an effective means of controlling fine...
-
Article
Open AccessP62 promotes FSH-induced antral follicle formation by directing degradation of ubiquitinated WT1
In females, the pathophysiological mechanism of poor ovarian response (POR) is not fully understood. Considering the expression level of p62 was significantly reduced in the granulosa cells (GCs) of POR patien...
-
Article
The maximum 3-star packing problem in claw-free cubic graphs
A 3-star is a complete bipartite graph \(K_{1,3}\) K ...
-
Article
Analysis and Modeling of Intermittent Fluctuation Mechanisms of Piezoelectric Impact-Induced Vibration Cantilever Energy Harvester
Piezoelectric impact-induced vibration cantilever energy harvesters for conventional energy have low ambient vibration frequencies. Expanding the response bandwidth of vibratory energy harvesters and improving...
-
Article
Clinical features and mutational spectrum of Chinese patients with primary hyperoxaluria type 2
Primary hyperoxaluria type 2 (PH2) is a rare hereditary disease that causes nephrolithiasis, nephrocalcinosis and kidney failure. This study aimed to investigate the clinical features and mutational spectrum o...
