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Article
miRNAs promote generation of porcine-induced pluripotent stem cells
The pigs have similarities of organ size, immunology and physiology with humans. Porcine-induced pluripotent stem cells (piPSCs) have great potential application in regenerative medicine. Here, we established ...
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Article
Effects of WT1 gene downregulation on apoptosis in porcine fetal fibroblasts
Wilms’ tumor gene 1 (WT1) is located on chromosome 11p13. Besides a role in the development of Wilms’ tumor, specific mutations in the Zn finger region are found in Denys-Drash syndrome and Frasi...
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Article
Sodium butyrate-induced histone hyperacetylation up-regulating WT1 expression in porcine kidney fibroblasts
Wilms’ tumor 1 gene (WT1) is essential for the development of kidney and histone acetylation and is involved in its expression regulation in mice. However, whether WT1 expression is associated with histone acetyl...