1,246 Result(s)
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Wenqi **ao
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Clinical characteristics and prognosis of pancreatitis associated with immune checkpoint inhibitors
Immune checkpoint inhibitors (ICIs) have shown remarkable efficacy against various cancers in clinical practice. However, ICIs can cause immune checkpoint inhibitor-associated pancreatic injury, often leading ...
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Multikingdom and functional gut microbiota markers for autism spectrum disorder
Associations between the gut microbiome and autism spectrum disorder (ASD) have been investigated although most studies have focused on the bacterial component of the microbiome. Whether gut archaea, fungi and...
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Open AccessTelomere-to-telomere genome assembly of the goose Anser cygnoides
Our study presents the assembly of a high-quality Taihu goose genome at the Telomere-to-Telomere (T2T) level. By employing advanced sequencing technologies, including Pacific Biosciences HiFi reads, Oxford Nan...
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Open AccessA single-cell chromatin accessibility dataset of human primed and naïve pluripotent stem cell-derived teratoma
Teratoma, due to its remarkable ability to differentiate into multiple cell lineages, is a valuable model for studying human embryonic development. The similarity of the gene expression and chromatin accessibi...
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Remodel the perifollicular microenvironment via Minoxidil-loaded microneedle patch and cold atmospheric plasma for treating androgenetic alopecia
Androgenetic alopecia (AGA) is a chronic and progressive form of hair loss characterized by vascular degeneration in the perifollicular microenvironment, leading to cell apoptosis and eventual loss of hair fol...
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Fine map** and identification of a Fusarium wilt resistance gene FwS1 in pea
A Fusarium wilt resistance gene FwS1 on pea chromosome 6 was identified and mapped to a 91.4 kb region by a comprehensive genomic-based approach, and the gene Psat6g003960 harboring NB-ARC domain was identified a...
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Open-Vocabulary Animal Keypoint Detection with Semantic-Feature Matching
Current image-based keypoint detection methods for animal (including human) bodies and faces are generally divided into fully supervised and few-shot class-agnostic approaches. The former typically relies on l...
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Open AccessCombined clinical significance of MRI and serum mannose-binding lectin in the prediction of spinal tuberculosis
Spinal tuberculosis (STB) is a local manifestation of systemic infection caused by Mycobacterium tuberculosis, accounting for a significant proportion of joint tuberculosis cases. This study aimed to explore t...
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Fine map** and transcriptome profiling reveal CpAPRR2 to modulate immature fruit rind color formation in zucchini (Cucurbita pepo)
A large fragment deletion of CpAPRR2, encoding a two-component response regulator-like protein, which influences immature white rind color formation in zucchini (Cucurbita pepo).
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A Hybrid SBP-SAT/Fourier Pseudo-spectral Method for the Transient Wigner Equation Involving Inflow Boundary Conditions
In this paper, a hybrid SBP-SAT/pseudo-spectral method is proposed for solving the time-dependent Wigner equation. High-order summation-by-parts (SBP) operators are utilized to discretize the Wigner equation s...
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Open AccessALKBH4 impedes 5-FU Sensitivity through suppressing GSDME induced pyroptosis in gastric cancer
5-Fluorouracil (5-FU) is the primary treatment option for advanced gastric cancer. However, the current challenge lies in the absence of validated biomarkers to accurately predict the efficacy and sensitivity ...
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Open AccessStability evaluation of open-pit mine slope based on Bayesian optimization 1D-CNN
As mechanized open-pit coal mining intensifies, assessing and predicting slope stability has become increasingly important. To address the limitations of traditional mechanical calculations, numerical simulati...
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Open AccessTransformer fusion-based scale-aware attention network for multispectral victim detection
The aftermath of a natural disaster leaves victims trapped in rubble which is challenging to detect by smart drones due to the victims in low visibility under the adverse disaster environments and victims in v...
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Open AccessIsorhapontigenin inhibition of basal muscle-invasive bladder cancer attributed to its downregulation of SNHG1 and DNMT3b
Bladder cancer (BC) is among the most prevalent malignant urothelial tumors globally, yet the prognosis for patients with muscle-invasive bladder cancer (MIBC) remains dismal, with a very poor 5-year survival ...
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CT-based radiomics of machine-learning to screen high-risk individuals with kidney stones
Screening high-risk populations is crucial for the prevention and treatment of kidney stones. Here, we employed radiomics to screen high-risk patients for kidney stones. A total of 513 independent kidneys from...
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Open AccessNitrogen-doped hollow carbon sphere composite Mn3O4 as an advanced host for lithium-sulfur battery
As the most promising advanced energy storage system, lithium-sulfur batteries (LSBs) are highly favored by the researchers because of their advantages of high energy density (2500 W h kg−1), low cost and non-pol...
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Open AccessAssociation of serum fatty acid pattern with depression in U.S. adults: analysis of NHANES 2011–2012
Exposure to different concentration levels of fatty acids (FAs) may have an impact on depression. However, previous studies using individual FAs may not reflect the performance of mixtures of various FAs, and ...
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Open AccessKriging-based surrogate data-enriching artificial neural network prediction of strength and permeability of permeable cement-stabilized base
Limited test data hinder the accurate prediction of mechanical strength and permeability of permeable cement-stabilized base materials (PCBM). Here we show a kriging-based surrogate model assisted artificial n...
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Open AccessBlack TiO2-based nanoparticles as Toll-like receptor stimulator delivery system for enhanced photothermal-immunotherapy of pancreatic cancer
The tumor-specific immune responses, essential for removing residual lesions and preventing tumor metastases, can be stimulated by tumor-associated antigens (TAAs) released following photothermal therapy (PTT)...
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A tailored ratiometric fluorescent sensor based on CdTe and MgF2 quantum dots for trace N-ethylpentylone detection
The development of low-cost and highly sensitive ratiometric fluorescence sensor, CdTe@MIPs/MgF2, for N-Ethylpentylone (NEP) detection in wastewater samples is described. In this system, CdTe@MIPs (λex = 370, λem...
