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  1. No Access

    Article

    SUMOylation of RNF146 results in Axin degradation and activation of Wnt/β-catenin signaling to promote the progression of hepatocellular carcinoma

    Aberrant SUMOylation contributes to the progression of hepatocellular carcinoma (HCC), yet the molecular mechanisms have not been well elucidated. RING-type E3 ubiquitin ligase RNF146 is a key regulator of the...

    Wenjia Li, Qingfang Han, Yuanxin Zhu, Yingshi Zhou, **gyuan Zhang, Weijun Wu… in Oncogene (2023)

  2. No Access

    Article

    Development of a 48-Well Dynamic Suspension Culture System for Pancreatic Differentiation from Human Embryonic Stem Cells

    Human pluripotent stem cells (hPSCs) have started to emerge as a potential tool with application in fields of drug discovery, disease modelling and cell therapy. A variety of protocols for culturing and differ...

    Yizhe Song, **aoqian Chen, Decan Liang, **g Liu… in Stem Cell Reviews and Reports (2022)

  3. Article

    Open Access

    Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling

    Alpha-lipoic acid (α-LA), a well-known antioxidant, was proved to active ALDH2 in nitrate tolerance and diabetic animal model. However, the therapeutic advantage of α-LA for heart failure and related signaling...

    Wenjia Li, Lei Yin, **aolei Sun, Jian Wu, Zhen Dong, Kai Hu… in Cell Death & Disease (2020)

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  4. No Access

    Article

    Mitochondrial DNA genetic polymorphism in thirteen rice cytoplasmic male sterile lines

    Thirteen rice CMS lines derived from different cytoplasms were classified into eight groups by PCR amplification on mtDNA. The orf79 gene,...

    Ji Luan, Tianran Liu, Weiqi Luo, Wen Liu, Minqi Peng, Wenjia Li… in Plant Cell Reports (2013)